Influence of Cinnamomum camphora ethanolic extract on Biophysical and Biochemical Parameters of Cutaneous Wounds in Rats

  • Praveen Kumar Sen Research Scholar, Department of Pharmacy Sunrise University Alwar Rajasthan, India
  • Shiv Garg Research Supervisor, Department of Pharmacy Sunrise University Alwar Rajasthan, India

Abstract

The ethanolic extract of Cinnamomum camphora leaves (100mg/kg/day for 16 days) was evaluated for its wound healing activity in rats using excision, incision and dead space wound models. Extract treated animal’s exhibit 95% reduction in wound area when compared to controls which was 84%. The extract treated wounds are found to epithelize faster as compared to controls. The wet and dry granulation tissue weight including Hydroxyproline, elastin and collagen tissue content increased significantly (P< 0.001) when compared with control.


Keywords: Excision wound, Dead space wound, incision, Hydroxyproline, elastin, collegan

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Sen PK, Garg S. Influence of Cinnamomum camphora ethanolic extract on Biophysical and Biochemical Parameters of Cutaneous Wounds in Rats. JDDT [Internet]. 16Jan.2020 [cited 18Jun.2021];9(4-s):1169-72. Available from: https://jddtonline.info/index.php/jddt/article/view/3833