An Overview : Natural Bio-enhancer’s in Formulation Development

  • Chander Pal Singh Verma Faculty of Pharmaceutical Sciences, Motherhood University, Roorke , Uttharakhand, India
  • Santosh Verma Faculty of Pharmaceutical Sciences, Motherhood University, Roorke , Uttharakhand, India
  • Mahendra Singh Ashawat Laureate Institute of Pharmacy, VPO Kathog, Jwalamukhi, Dist. Kangra, Himachal Pradesh, India
  • Vinay Pandit Laureate Institute of Pharmacy, VPO Kathog, Jwalamukhi, Dist. Kangra, Himachal Pradesh, India


Bioenhancers are chemical entities that are obtained from synthetic as well as natural sources. They are mainly used in formulation development to enhance the bioavailability of poorly solubilized drug molecule. The ideal characteristic of bioenhancers includes inertness, nontoxic, cost effective and decrease the dose of active constituents. There are lots of natural bioenhancers available such as piperine quercetin niaziridin, genistein, glycrrhyzin, curcumin. The review focus on plant based bioenhancers and their active principle that produces those effects. There is a need of extensive study on natural bioenhancers which can be utilized in formulation development.

Keywords: bioenhancer, bioavailability, piperine, curcumin


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How to Cite
Verma C, Verma S, Ashawat MS, Pandit V. An Overview : Natural Bio-enhancer’s in Formulation Development. JDDT [Internet]. 15Nov.2019 [cited 18May2021];9(6):201-5. Available from: