Design and Optimization of Mefenamic acid Fast Dissolving Tablets Employing Modified Starch by 23 Factorial Design

Authors

  • Rada Santosh Kumar GITAM Institute of Pharmacy, GITAM (Deemed to be University)
  • A. Suresh

Abstract

Latest developments in the technology have promoted viable dosage alternatives through oral route for pediatrics, bed ridden, and nauseous patients. Patient preference is one of the most important aspects in pharmacy practice. Now a day’s pharmacy companies are coming up with innovative drug delivery systems to deliver the drugs efficiently and with less side effects. This innovation led to the introduction of the concept of fast dissolving tablets. Though, a wide range of superdisintegrant is available for formulation of fast dissolving tablets. Still there is continuous need of development of superdisintegrants. Therefore in the present investigation, starch based superdisintegrant was prepared and evaluated for its application in the design of fast dissolving dosage forms.

Keywords: Fast Dissolving Tablets, Superdisintegrant, Modified Starch, Mefenamic acid.

DOI

https://doi.org/10.22270/jddt.v9i4-s.3622

Author Biographies

Rada Santosh Kumar, GITAM Institute of Pharmacy, GITAM (Deemed to be University)

GITAM Institute of Pharmacy, GITAM (Deemed To Be University) Rushikonda, Visakhapatnam-530045, Andhra Pradesh, India.

A. Suresh

GITAM Institute of Pharmacy, GITAM (Deemed To Be University) Rushikonda, Visakhapatnam-530045, Andhra Pradesh, India.

References

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Chaudhari PD, chaudhari SP, Kolhe SR, Davekv, More DM. Formulation and Evaluation of Fast Dissolving Tablets of Piroxicam, Indian Drugs, 2005; 42(10):641-9.

Bi Yx, Sunada H, Yonezawa Y, Danjo K, Evaluation of Rapidly Disintegration Tablets by Direct Compression Method Drug Delivery Indian Pharm, 1999; 25(5):571-98.

Bhagwati ST, Hiremath SN, Sreenivas SA, Comparative Evaluation of Disintegrants by FormulationgCefixames Dispersible Tablets, Indian Journal of Pharm Education, 2005; 39(4):194-7.

Published

25-08-2019
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How to Cite

1.
Santosh Kumar R, Suresh A. Design and Optimization of Mefenamic acid Fast Dissolving Tablets Employing Modified Starch by 23 Factorial Design. J. Drug Delivery Ther. [Internet]. 2019 Aug. 25 [cited 2025 Feb. 15];9(4-s):933-44. Available from: https://jddtonline.info/index.php/jddt/article/view/3622

How to Cite

1.
Santosh Kumar R, Suresh A. Design and Optimization of Mefenamic acid Fast Dissolving Tablets Employing Modified Starch by 23 Factorial Design. J. Drug Delivery Ther. [Internet]. 2019 Aug. 25 [cited 2025 Feb. 15];9(4-s):933-44. Available from: https://jddtonline.info/index.php/jddt/article/view/3622

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