In-Vivo Studies on Anti-Diabetic Potential of Leucas Aspera in Streptozotocin Induced Diabetic Wistar Albino Rats

  • GC Madhu
  • Kannaiyan Jaianand
  • K Rameshkumar
  • Paulraj Balaji
  • Veeramani Veeramanikandan


Nanotechnology is being a utilized in medicine for diagnosis, therapeutic drug delivery and for the development of treatment for many ailments and disorders specifically in the areas of drug delivery, as medical diagnostic tools, and as diseases cure agents. During the past decades, the biosynthesis of metal nanoparticles has received considerable attention due to the growing need to develop environmentally sociable technologies in material synthesis. In this study, we investigated the anti-diabetic potential of Leucas aspera leaf extract in streptozotocin-induced diabetic Wistar albino rats and, serum creatinine, blood urea, protein content, enzymatic antioxidant, and non-enzymatic antioxidant was estimated.  This study evidenced the efficacy of the anti-diabetic potential of Leucas aspera leaf extract in the in-vivo model.

Keywords: Diabetes mellitus, Iron oxide nanoparticles, Leucas aspera, Streptozotocin (STZ).


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Madhu G, Jaianand K, Rameshkumar K, Balaji P, Veeramanikandan V. In-Vivo Studies on Anti-Diabetic Potential of Leucas Aspera in Streptozotocin Induced Diabetic Wistar Albino Rats. JDDT [Internet]. 15Aug.2019 [cited 18Jun.2021];9(4-s):105-10. Available from: