Probiotics, their Health Benefits and Applications for Development of Human Health: A Review
Gastrointestinal microbial flora plays a major role in health of host. The person with the healthy digestive system is the indication of proper health. Probiotics bacteria are live nonpathogenic microorganism which has beneficial effects on host gastrointestinal tract which is mentioned in articles viz. Recent Advances in Pharmaceutical Approaches to Colon Specific Drug Delivery. Optimum population of probiotics bacteria are essential for the maintenance and effective functioning of the digestive system. Hence probiotics are the good therapeutic agents for the various abnormal conditions of gastrointestinal tract such as inflammatory bowel disease, chrohn’s disease, colon cancer etc. Probiotic micro biota also fights against pathogenic infections of GIT such as H. pylori infection by production of some antimicrobial chemical secretions such as bacteriocin. Recent studies and innovations and studies found that the probiotic bacteria are beneficial in the prevention and curative treatment of various disease and disorders like colorectal cancer, infection of urinary tract (UTI), allergic condition, cardiovascular disorders and depressive disorders. Probiotics are administered as nutraceutical products in the form of both conventional pharmaceutical dosage forms and traditional non-conventional food products, inclusion complexes with cyclodextrins effectively, sustained release tablets by solid dispersion technology etc. Probiotics are significantly gaining popularity due their wide application and safety. This paper presents the comprehensive review on the probiotics profile along with its some therapeutic applications, delivery approaches and current aspects.
Keywords: Probiotics, mechanisms, Health benefits, cardiovascular disorders, safety, colon targeted drug delivery system.
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).