An Approach to Evaluate Anti-arthritic and Thrombolytic Activity of Different parts of Solanum torvum Sw. (Solanaceae) and Smilax zeylanica L. (Liliaceae)

  • Md. Samsur Rahaman (1). Institute of Radiation and Polymer Technology, Bangladesh Atomic Energy Commission, Savar, Dhaka-1349. (2). Jagannath University, Dhaka-1100.
  • Md. Saifur Rahaman Senior Scientific Officer, Institute of Nuclear Science and Technology, Bangladesh Atomic Energy Commission, Savar, Dhaka-1349
  • Md. Abdul Bari Institute of Food and Radiation Biology, Bangladesh Atomic Energy Commission, Savar, Dhaka-1349
  • Rajesh Barua (1). Institute of Radiation and Polymer Technology, Bangladesh Atomic Energy Commission, Savar, Dhaka-1349. (2). Memorial University, Newfoundland, Canada.
  • Jahid Md. Mahbub Islam (1). Institute of Radiation and Polymer Technology, Bangladesh Atomic Energy Commission, Savar, Dhaka-1349. (2). Monash University, Malaysia.
  • Md. Siddiqul Islam Southeast University, Banani, Dhaka.
  • Mubarak Ahmad Khan Institute of Radiation and Polymer Technology, Bangladesh Atomic Energy Commission, Savar, Dhaka-1349.

Abstract

Phytochemical screening of chloroform and methanolic extracts of different parts of Solanum torvum and Smilax zeylanica was done. In vitro thrombolytic and anti-arthritic activities were assessed using the clot lysis method and egg albumin denaturation technique respectively. Between the chloroform and methanolic extracts, Chloroform extracts of both plants showed higher clot lysis activities (at 100 ppm solution). On the other hand, extracts of both plants performed better in terms of anti-arthritic activities (at 500 ppm solution). In the case of thrombolytic activity, between the plant extracts, the performance of S. torvum is higher compared to S. zeylanica plant. Among chloroform extracts of different plant parts, stem of S. torvum and root of S. zeylanica showed the highest, 35.44±1.89 % and 33.63±0.83 % activities respectively. Whereas, among the methanolic extracts of the plants, the root extracts of both plants showed the highest activities, 31.96±2.86 % for S. torvum and 32.01±1.46 % for S. zeylanica. In the case of anti-arthritic activity, the performance of S. zeylanica plant extracts is higher compared to that of S. torvum. Methanolic extract of leaf of S. zeylanica samples showed the best protein denaturation activity (52.38±2.12 %) followed by the Methanolic extract of stem sample of S. torvum  (44.29±2.14 %).

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Author Biographies

Md. Samsur Rahaman, (1). Institute of Radiation and Polymer Technology, Bangladesh Atomic Energy Commission, Savar, Dhaka-1349. (2). Jagannath University, Dhaka-1100.

Researcher

Md. Abdul Bari, Institute of Food and Radiation Biology, Bangladesh Atomic Energy Commission, Savar, Dhaka-1349

Senior Scientific Officer

Rajesh Barua, (1). Institute of Radiation and Polymer Technology, Bangladesh Atomic Energy Commission, Savar, Dhaka-1349. (2). Memorial University, Newfoundland, Canada.

Researcher

Jahid Md. Mahbub Islam, (1). Institute of Radiation and Polymer Technology, Bangladesh Atomic Energy Commission, Savar, Dhaka-1349. (2). Monash University, Malaysia.

Researcher

Md. Siddiqul Islam, Southeast University, Banani, Dhaka.

Assistant Professor

Mubarak Ahmad Khan, Institute of Radiation and Polymer Technology, Bangladesh Atomic Energy Commission, Savar, Dhaka-1349.

Researcher

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How to Cite
1.
Rahaman MS, Rahaman MS, Bari MA, Barua R, Islam JMM, Islam MS, Khan MA. An Approach to Evaluate Anti-arthritic and Thrombolytic Activity of Different parts of Solanum torvum Sw. (Solanaceae) and Smilax zeylanica L. (Liliaceae). JDDT [Internet]. 15Aug.2019 [cited 18Jun.2021];9(4-s):155-64. Available from: https://jddtonline.info/index.php/jddt/article/view/3186