Application of Silica Supported Aluminium Hydroxide as a Low Cost Green Catalyst for the One Pot MCR Sythesis via Thermal Method

  • Jayaveersinh Mahida
  • Ravi B. Patel


The catalysis is the first and active side they are good yield with good reusability. The sequence of time. They are the time of reaction is smaller, it saves the energy and time consummation, another thing is the good catalyst is intelligent for the dynamic yield but are focused on the design the catalyst they have good effectiveness as well as good reusability with green chemistry concept. In today times much, research is being carried out on Nano particles green catalysis we have eco-friendly make an endeavoured for designing new catalyst from waste aluminium foil to new catalyst. So our catalyst is designed from waste aluminium foil and transformed into good and reusability catalyst. They are continuing produced the same yield up to 7-8 reaction cycle.

Keywords: ketone, Aromatic aldehydes & ammonium hydroxide hydrochloride, green path with help of silica supported catalyst.


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Author Biographies

Jayaveersinh Mahida

Shree P.M. Patel institute of P.G. Studies & Research in science, Anand, Gujarat, India

Ravi B. Patel

Shree P.M. Patel institute of P.G. Studies & Research in science, Anand, Gujarat, India


[1] Facile, eco-friendly and one-pot synthesis of 3,4-disubstitutedisoxazol- 5(4H)-ones using starch solution as a reaction mediaRH Vekariya, HD Patel - 2017 -
[2] N Hazeri, MT Maghsoodlou, F Mir, M Kangani; An efficient one-pot three-component synthesis of tetrahydrobenzo [b] pyran and 3, 4-dihydropyrano [c] chromene derivatives using starch solution as catalyst Chinese Journal of …, 2014 - Elsevier
[3] Kumari, M Rajeswari, JM Khurana , A Green Approach for the Synthesis of Novel 7, 11-Dihydro-6H-chromeno [3, 4-e] isoxazolo [5, 4-b] pyridin-6-one Derivatives Using Acidic Ionic Liquid [C4mim][HSO4]S - Australian Journal of Chemistry, 2016 - CSIRO
[4]DABCO as a mild and efficient catalyst for the synthesis of tetrahydropyrimidines N Foroughifar, A Mobinikhaledi, B Rabeie, L Jalili - Rev Roum Chim, 2013 -
[5] An efficient synthesis of stable phosphorus ylides derived from triphenylphosphine, dialkyl acetylenedicarboxylates, and an NH-AcidMT Maghsoodlou, N Hazeri , Sulfur, and Silicon, 2006 - Taylor & Francis
[6] One-pot multicomponent synthesis of highly substituted piperidines using p-toluenesulfonic acid monohydrate as catalyst
SS Sajadikhah, MT Maghsoodlou, N Hazeri… - Monatshefte für Chemie …, 2012 - Springer
[7] DABCO as a mild and efficient catalyst for the synthesis oftetrahydropyrimidinesN Foroughifar, A Mobinikhaledi, B Rabeie, L Jalili - Rev Roum Chim, 2013 -
[8] R Tayebee, MM Amini, M Ghadamgahi ; H5PW10V2O40/Pip-SBA-15: A novel reusable organic–inorganic hybrid material as potentLewisacid catalyst for one-pot solvent-free synthesisof3,4-dihydropyrimidinones Journal of Molecular …, 2013 - Elsevier
[9] Safaei-Ghomi, J., Javidan, A., Ziarati, A. et al. J Nanopart Res (2015) 17: 338.
[10] Zhu Y, Xie M, Dong S, Zhao X, Lin L, Liu X, Feng X (2011) Asymmetric cycloaddition of b, g-unsaturated a-ketoesters with electron-rich alkenes catalyzed by a chiral Er(OTf)3/N, N´-dioxide complex: highly enantioselective synthesis of 3,4-dihydro-2H-pyrans. Chem Eur J 17:8202–8208
[11] Wag Y, Xin X, Liang Y, Lin Y, Duan H, Dong D (2009) N, N, N´, N´-tetramethylchloroformamidinium chloride-mediated cyclizations of β-oxo amides: facile and divergent one-pot synthesis of substituted 2H-pyrans, 4H-pyrans and pyridin-2(1H)-ones. Adv Synth Catal 351:2217–2223
[12] Venkatesham A, Rao RS, Nagaiah K, Yadav JS, RoopaJones G, Basha SJ, Sridhar B, Addlagatta A (2012) Synthesis of new chromeno-annulated cis-fused pyrano[3,4-c]pyran derivatives via domino Knoevenagel-hetero-Diels-Alder reactions and their biological evaluation towards antiproliferative activity. Med Chem Commun 3:652–658
[13] Saundane AR, Vijaykumar K, Vaijinath AV (2013) Synthesis of novel 2-amino-4-(5′-substituted 2′-phenyl-1H-indol-3′-yl)-6-aryl-4H-pyran-3-carbonitrile derivatives as antimicrobial and antioxidant agents. Bioorg Med Chem Lett 23:1978–1984
[14] Safaei-Ghomi J, Shahbazi-Alavi H, Heidari-Baghbahadorani E (2014) SnO nanoparticles as an efficient catalyst for the one-pot synthesis of chromeno[2,3-b]pyridines and 2-amino-3,5-dicyano-6-sulfanyl pyridines. RSC Adv 4:50668–50677
[15] Safaei-Ghomi J, Kalhor S (2015) A convenient synthesis of 2-aminocyclohex-1-ene-1-carboxylic esters by FeCl3/SiO2 nanoparticles as robust and efficient catalyst. Chin Chem Lett 26:735–738.
[16] Patil SA, Wang J, Li XS, Chen JJ, Jones TS, Hosni-Ahmed A, Patil R, Seibel WL, Li W, Miller DD (2012) New substituted 4H-chromenes as anticancer agents. Bioorg Med Chem Lett 22:4458–4461.
[17] Naeimi H, Rashid Z, Zarnani AH, Ghahremanzadeh R (2014) Nanocrystalline magnesium oxide: an efficient promoter and heterogeneous nano catalyst for the one-pot synthesis of pyrazolotriazoles in green medium. J Nanoparticle Res 16:2416
186] Kumar D, Reddy VB, Sharad S, Dube U, Kapur S (2009) A facile one-pot green synthesis and antibacterial activity of 2-amino-4H-pyrans and 2-amino-5-oxo-5,6,7,8-tetrahydro-4H-chromenes. Eur J Med Chem 44:3805–3809
[19] Chen WB, Wu ZJ, Pei QL, Cun LF, Zhang XM, Yuan WC (2010) Highly enantioselective construction of spiro[4H-pyran-3,3′-oxindoles] through a Domino Knoevenagel/Michael/Cyclization sequence catalyzed by cupreine. Org Lett 12:3132–3135
[28]Banerjee S, Horn A, Khatri H, Sereda G (2011) A green one-pot multicomponent synthesis of 4H-pyrans and polysubstituted aniline derivatives of biological, pharmacological, and optical applications using silica nanoparticles as reusable catalyst. Tetrahedron Lett 52:1878–1881
[20] Maddila, Suresh; Jonnalagadda, Sreekantha B.; Gangu, Kranthi K.; Recent Advances in the Synthesis of Pyrazole Derivatives Using MulticomponentReactionsBottom of Form Current Organic Synthesis, Volume 14, Number 5, August 2017, pp. 634-653(20).
[21] Maleki, A., Jafari, A.A.& Yousefi, S. JIRANCHEMSOC(2017) 14:1801.
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How to Cite
Mahida J, Patel RB. Application of Silica Supported Aluminium Hydroxide as a Low Cost Green Catalyst for the One Pot MCR Sythesis via Thermal Method. JDDT [Internet]. 15Aug.2019 [cited 18Jun.2021];9(4-s):43-7. Available from: