THE VISHAGHNA PROPERTIES OF MANJISHTHA (Rubia cordifolia) IN AYURVEDIC AND CONTEMPORARY SCIENCE: AN OVERVIEW

  • Rohit Kumar Khatik M.D., AMO, I/c Lecturer, department of Agad Tantra Vyavahar Ayurved & Vidhi Vaidyak, Govt. (Auto.) Ashtang Ayurved College Lokmanya Nagar, Indore (M.P.) 452009, India
  • Ashish Khatik AMO, Government Ayurved Dispensary, Bareli, Raisen (M.P.), India
  • Anita Sharma H.O.D & Professor, Dept. Of Agad Tantra & Vyavhara Ayurved National Institute Of Ayurved, Jaipur 302002, India

Abstract

The present concept is given to help for to establish as bridge between Ayurveda and contemporary science. The Concept of Ayurvedic vishaghna properties is near about detoxifying action (Antidote action) in modern era. It is may be beneficial integrated concept for metabolic toxicity, substance acquired acute and chronic toxicity, biological toxicity, cumulative toxicity etc. and it also help to understand the detoxifying phenomenon. The single and multiple preparations of manjistha are available which indicates its utility in many poisoning. All aspects of manjishtha are studied in detail especially in field of detoxification. Selection of all logical references are done and collection, correlation and explanation as per requirement. According to indication and detoxifying therapeutic use of manjishtha are highlights, which described especially in Ayurvedic and modern text. All ayurvedic and contemporary references regarding vishaghna are collected from Ayurvedic fundamental books and various textbooks, research article, international journals. Theoretically, it will breakdown the pathogenesis of toxicity and progress forward to denaturized any poison. It can be useful for disease which comes under area of any field of toxicity. We can prevent and treat much toxicological disorder. On the basis of concept of vishaghana properties of manjishtha, it can be broadly used in today’s era for preventive as well as curative disease free life from toxicological agent.


Keywords; manjishtha, vishaghana properties, detoxifying uses

Downloads

Download data is not yet available.

Author Biographies

Rohit Kumar Khatik, M.D., AMO, I/c Lecturer, department of Agad Tantra Vyavahar Ayurved & Vidhi Vaidyak, Govt. (Auto.) Ashtang Ayurved College Lokmanya Nagar, Indore (M.P.) 452009, India

M.D., AMO, I/c Lecturer, department of Agad Tantra Vyavahar Ayurved & Vidhi Vaidyak, Govt. (Auto.) Ashtang Ayurved College Lokmanya Nagar, Indore (M.P.) 452009, India

Ashish Khatik, AMO, Government Ayurved Dispensary, Bareli, Raisen (M.P.), India

AMO, Government Ayurved Dispensary, Bareli, Raisen (M.P.), India

Anita Sharma, H.O.D & Professor, Dept. Of Agad Tantra & Vyavhara Ayurved National Institute Of Ayurved, Jaipur 302002, India

H.O.D & Professor, Dept. Of Agad Tantra & Vyavhara Ayurved National Institute Of Ayurved, Jaipur 302002, India

References

1. Bhatt P et al; Rubia cordifolia overview: A New Approach to treat cardiac disorders, Int. J. Drug Dev. & Res., April-June 2013; 5(2):47-54.
2. Sukh Dev: A selection of Prime Ayurvedic plant drugs Ancient-Modern Concordance. New Delhi: Anamaya publishers; 2006
3. Shukla V, Tripathi R, Charak S, sutrasthan 4/8(8), Choukhamba Sanskrit Pratishthan Delhi; 2006,p;72
4. Shukla V, Tripathi R, Charak S, sutrasthan 4/8(11), Choukhamba Sanskrit Pratishthan Delhi; 2006,p;73
5. Shukla V, Tripathi R, Charak S, sutrasthan 4/8(39), Choukhamba Sanskrit Pratishthan Delhi; 2006, p;76
6. Shastri A, Sushruta samhita sutrasthan 38/45, Choukhamba Sanskrit sansthan, Varanasi; 2007, p;144
7. Shastri A, Sushruta samhita sutrasthan 38/8, Choukhamba Sanskrit sansthan, Varanasi; 2007, p;148
8. Tripathi R, Ashtang samgraha sutrasthan 15/21, Choukhamba Sanskrit Pratishthan Delhi; 2001, p;300
9. Tripathi R, Ashtang samgraha sutrasthan 15/38, Choukhamba Sanskrit Pratishthan Delhi; 2001, p;306
10. Tripathi R, Ashtang samgraha sutrasthan 16/31, Choukhamba Sanskrit Pratishthan Delhi; 2001, p;320
11. Chunekar K, Bhavaprakash N, Haritkyadi varga 191, Chaukhamba bharti academy Varanasi; 2010, p;107
12. Tripathi I, Raj N, pippalyadi varga 190-193, Chaukhamba Krishnadas academy Varanasi;2010,p;173-174
13. Sharma P, Sharma G, Kaidev N, Aushadhi varga 1424-1427, 1st edition Chaukhamba Orientalia Varanasi; 1979, p;264
14. Ojha J, Mishra U, Dhanwantari N, guduchayadi varga 17-18, Chaukhamba Surbharti prakashan Varanasi;2004,p;107
15. Sharma P, Priya N, Pippalyadi varga 76, 1st edition Chaukhamba Surbharti prakashan Varanasi;2004,p;19
16. Itokawa H, QiaoY, Takeya K. Anthraquinones and naphthohydroquinone from Rubia cordifolia phytochemistry.1989; 28(12):3465-3468
17. Rao GMM, Rao CV, PushpangadanP, Shirwaikar A, Hepatoprotective effects of rubiadin, a major constituent of rubia cordifolia Linn. Journal of Ethnopharmacology, 2006; 103(3)484-490.
18. Li X, Liu Z, Chen Y, Wang LJ, Zhen YN, Sung GZ and Ruan CC, Rubiacardone, A new anthroqinone glycosides from roots of rubia cordifolia. Molecules, 2009; 14:566-572.
19. Chang LC, Chavez D, Gills JJ, Fongs HHS, Pezzuto JM, Kinghorn AD, Rubiasins A-C, new anthracene derivatives from the roots and stem of rubia cordifolia. Tetrahedron Lett. 2000; 41(37); 7157-7162.
20. Arisawa M, Ueno H, Nimura M, Hayashi T, MoritaN. Rubiatriol, a new triterpenoid from the chinese drug “Qian Cao Gen” Rubia cordifolia. Journal of Natural Products. 1986; 49(6):1114-1116
21. Talapatra SK, Sarkar AC, Talpatra B, two pentacylic triterpenes from Rubia Cordifolia Phytochemistry,1981; 20(8):1923-1927
22. Lodia S, Kansala L, antioxidant activity of rubia cordifola against lead toxicity, International journal of pharmaceutical science and research 2012; 3(7):2224-2232.
23. Tripathi YB, Singh AV, Role of Rubia cordifolia Linn. In radiation protection. Indian journal of Experimental Biology, 2007; 45(7):620-625.
24. Kaur P, Chandel M, Kumar S, Kumar N, Singh B, Kaur S, Modulatory role of alizarin from rubia cordifolia L. against genotoxicity of mutagens. Food and Chemical Toxicology, 2010; 48:320-325.
25. Joharapurkar AA, Zambad SP, Wanjari MM and Umathe SN: In vivo evaluation of antioxidant activity of alcoholic extract of Rubia cordifolia linn. and its influence on ethanol-induced Immunosuppression. Indian Journal of Pharmacology 2003; 35:232-236
26. Jun do Y, Han CR, Lee JY, Park W, Choi MS, Woo MH, Kim YH: Anti-Adipogenic Activity of 2-Carbomethoxy-2,3-Epoxy-3-Prenyl-1,4-Naphthoquinone from Rubia cordifolia L. Journal of Medicinal Food 2011; 14(5):454-61
27. Aslam M, Imtiyaz S, Tariq M, Chaudhary SS, Ahmed K, Unani immunomodulating drugs: An overview, Int.J.Med.Pharma.Sci.Res.Review, 2013; 1:1-10
28. Tripathi, B.Y. & Singh, V.A. Ind.J.Exp.Bio. 2007; 45:620-625
29. Thakur AK and Hamrapurkar PD: Quantitative densitometric HPTLC analysis of purpurin in the parts of Rubia cordifolia and in pharmaceutical dosage forms. Journal of Planar Chromatographic– Mode TLC 2009; 22(2):109-113
30. Basu S, Ghosh A, Hazra B: Evaluation of the antibacterial activity of Ventilago madraspatana Gaertn., Rubia cordifolia Linn. and Lantana camara Linn.: isolation of Emodin and Physcion as active antibacterial agents. Phytotherapeutic Research 2005; 19(10):888–894
31. Gorle, A. M. & Patil S. S. Der Pharmacia Sinica, 2010; 1(3):59-63
32. V., Chitra, Kumar K. P. Int.J. PharmTech Res. 2009; 1(4):1000-1009
33. Gilani AH, Janbaz KH: Effect of Rubia cordifolia extract on acetaminophen and CCl4-induced hepatotoxicity. Phytotheraphy Research 1995; 9(5):372–375
34. Antarkar SS, Chinwalla T, Bhatt N, Anti-inflammatory activity of rubia cordifolia Linn. In rats, Indian J. Pharmacol., 1983; 15:185-188.
35. Tripathi YB, Sharma M, Shukla S, Tripathi P, Thyagaraju K, Reddanna P, rubia cordifolia inhibits potato lipoxygenase, Indian J. Exp. Biol., 1995; 33:109-112.
Crossmark
Statistics
774 Views | 982 Downloads
How to Cite
1.
Khatik RK, Khatik A, Sharma A. THE VISHAGHNA PROPERTIES OF MANJISHTHA (Rubia cordifolia) IN AYURVEDIC AND CONTEMPORARY SCIENCE: AN OVERVIEW. JDDT [Internet]. 15Oct.2018 [cited 19May2024];8(5-s):12-5. Available from: https://jddtonline.info/index.php/jddt/article/view/1923
Section
Review