• Sunil Kumar Parajapati Dept. of Pharmacy, Bundelkhand University, Jhansi, India
  • Sheo Datta Maurya Dept. of Pharmacy, IEC Group of Institution, Greater Noida, India
  • Manas K Das Dept. of Pharmacy, IEC Group of Institution, Greater Noida, India
  • Vijay Kumar Tilak Dept. of Pharmacy, IEC Group of Institution, Greater Noida, India
  • Krishna Kr Verma Ram-Eish Institute of Pharmacy, Greater noida, India
  • Ram C Dhakar Jhalawar Medical College & Hospital, Jhalawar, India


This review gives concise information about the application of dendrimers in the field of drug delivery. Due to their unique architecture these have improved physical and chemical properties. Due to their terminal groups these show high solubility, miscibility and reactivity. Dendrimers have well defined size, shape, molecular weight and monodispersity. These properties make the dendrimers a suitable carrier in drug delivery application. Dendrimers are unimolecular miceller in nature and due to this enhances the solubility of poorly soluble drugs. Their compatibility with DNA, heparin and polyanions make them more versatile. Dendrimers, also referred as modern day polymers, they offer much more good properties than the conventional polymers. Due to their multivalent and mono disperse character dendrimers have stimulated wide interest in the field of chemistry biology, especially in applications like drug delivery, gene therapy and chemotherapy. Self assembly produces a faster means of generating nanoscopic functional and structural systems. But their actual utility in drug delivery can be assessed only after deep understanding of factors affecting their properties and their behavior in vivo.

Key words: Dendrimers, Drug targeting, nanoscale carriers.


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Author Biographies

Sunil Kumar Parajapati, Dept. of Pharmacy, Bundelkhand University, Jhansi, India
Professor, Dept. of Pharmacy, Bundelkhand University, Jhansi, India
Sheo Datta Maurya, Dept. of Pharmacy, IEC Group of Institution, Greater Noida, India

Dept. of Pharmacy, IEC Group of Institution, Greater Noida, India

Manas K Das, Dept. of Pharmacy, IEC Group of Institution, Greater Noida, India

Dept. of Pharmacy, IEC Group of Institution, Greater Noida, India

Vijay Kumar Tilak, Dept. of Pharmacy, IEC Group of Institution, Greater Noida, India

Dept. of Pharmacy, IEC Group of Institution, Greater Noida, India

Krishna Kr Verma, Ram-Eish Institute of Pharmacy, Greater noida, India

Ram-Eish Institute of Pharmacy, Greater noida, India

Ram C Dhakar, Jhalawar Medical College & Hospital, Jhalawar, India

Jhalawar Medical College & Hospital, Jhalawar, India


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Parajapati S, Maurya S, Das M, Tilak VK, Verma KK, Dhakar RC. POTENTIAL APPLICATION OF DENDRIMERS IN DRUG DELIVERY: A CONCISE REVIEW AND UPDATE. JDDT [Internet]. 14Mar.2016 [cited 4Dec.2021];6(2):71-8. Available from: https://jddtonline.info/index.php/jddt/article/view/1195

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