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Aralia armata (Wall.) Seem, a potential herb in treatment and complication recover therapy for stroke disease: A mini opinion and call for further research

¹Herbal medicine laboratory, Thai Nguyen University of Agriculture and Forestry, Thai Nguyen, Vietnam

Article Info:

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Article History:

Received 08 July 2023

Reviewed 21 July 2023

Accepted 29 July 2023

Published 15 August 2023

Abstract

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Based on our knowledge, experience and field survey in the treatment of stroke by complementary/alternative medicine and especially the herb therapy, we briefly commented on properties of curing ischemic stroke of Aralia armata (Wall.) Seem and suggest that the future research to insightfully educidate this science opinion is necessary.

Keywords: Aralia armata (Wall.), stroke disease, ischemic stroke

Cite this article as:

Le QU, Le TT, Aralia armata (Wall.) Seem, a potential herb in treatment and complication recover therapy for stroke disease: A mini opinion and call for further research , Journal of Drug Delivery and Therapeutics. 2023; 13(8):3-4 DOI: http://dx.doi.org/10.22270/jddt.v13i8.5930

*Address for Correspondence:

Quang-Ung Le, Herbal medicine laboratory, Thai Nguyen University of Agriculture and Forestry, Thai Nguyen, Vietnam

In Vietnam, the rate of stroke disease tends to increase in recent years and ischemic stroke is one of the leading causes of death and causing handicapped. Using herb therapy in the treatment and recovering complication of stroke disease has attracted substantial attention because it has beneficial efficacy more than western medicine.

Aralia armata has been used as traditional folk remedies with many benefits. Moreover, it’s young buds are consumed as a specialty vegetable. Root bark has effects of clearing heat toxin, wind dispelling, strong antibiotic. The stem core has a tonic effect. In Traditional Vietnamese Medicine, this herb is used for the treatment of arthritis, chronic cough, sore throat, tonsillitis and edema. The former chemical composition studies reported that root bark of Aralia armata has triterpenoid glucuronide saponin ¹, aramatosides A and B². It is interesting for stroke patients. The comsumption of Aralia armata (Wall.) Seem combined with some other herbs is claimed to be highly effective, which was recorded via interview on status of using herbs in the disease treatment at high-density ethnic minorities areas.

According to the theory of traditional medicine, herbal prescription strategy for the treatment of stroke was based on the theory of exogenous wind and guaranteing the functions of dispelling wind and cold, dilating blood vessels, inhibiting thrombosis, dissolving blood clots. Disclosed prescriptions include Saposhnikovia divaricata (Turcz. ex Ledeb.) Schischk, Zingiber officinale Roscoe, Aralia armata (Wall.) Seem, Pheretima praepinguis, Dioscorea tokoro Mahino, Blumea balsamifera (L.) DC., Prunus amygdalus Batsch, Camphorina cinnamomum (L.) Farw, Glycyrrhiza glabra L, Millettia reticulata L, in which Aralia armata (Wall.) Seem is main herbal with rate of over 20 percent of weight. The used part is stem core. Based on our knowledge and experience, Aralia armata (Wall.) Seem is used in this prescription with function of both Tonify Qi and increase Yang and dispelling wind. Moreover, in comparison of the data with the literature of herb compositions used to in the reported stroke treatment therapy, the main herbs were similar to composition of Xiaoxuming prescription³. Interestingly, after taking solution of herb extract about 30 days, stroke patients’s health quickly recovers and they are able to start walking.

Aralia armata (Wall.) Seem has attracted substantial attention because it was thought to have oustanding benefits for treatment of ischemic stroke and complication recover. Additionally, when it was used together with herbs, strong synergistic effect was stated by stroke patients. We hope that more comprehensive pharmacological mechanisms related to effect of stroke treatment of Aralia armata (Wall.) Seem need to be elucidated. Authors call for further research to determine the definitive mechanism and clinical trials should be caried out more to firm evidence.