INTERVENTIONS TO IMPROVE ADHERENCE TO ANTIRETROVIRAL MEDICATIONS
AntiretroviralÂ therapyÂ hasÂ ledÂ toÂ a substantialÂ reductionÂ inÂ HIV associatedÂ morbidity andÂ mortality. EfficacyÂ ofÂ antiretroviralÂ treatmentÂ in HIV/AIDS is showing inhibition of viralÂ replication andÂ reductionÂ ofÂ viralÂ loadÂ toÂ aÂ pointÂ whereÂ viral particlesÂ areÂ undetectableÂ inÂ theÂ bloodÂ ofÂ infected individuals. Increasing recognition of medication adherence is a crucial factor in treatment outcomes.Â This has led to the realization that HIV/AIDS is aÂ chronicÂ illnessÂ andÂ hence theÂ quality of Â lifeÂ ofÂ PLWHAÂ needsÂ toÂ beÂ enhanced. TheÂ maintenanceÂ ofÂ viralÂ suppressionÂ requiresÂ maximum adherenceÂ (atÂ leastÂ 95%)Â toÂ ART.
The objective of this review was to assess the recent literatures regarding interventions to improve antiretroviral medication adherence; to know factors affecting adherence, strategies to measure adherence to ART by reviewing research works done recently (2008-2013) on intervention to improve ARV adherence (adherence improving tools and strategies).
This literature review was obtained from electronic search on pubmed, AIDS LINES, MEDILINE, PyschInfo and also search was conducted on individual journals and manuals.
Adherence to ART is closely tied to virologic, immunologic, and clinical outcomes. Improving adherence requires collaborating with the patient in an effort to understand and ameliorate individual impediments to adherence, generally by establishing dedicated time with every patient to educate, plan for adherence, and maintain support and collaboration throughout the course of treatment.
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