• Tesfaye Dalalo Gabriel Addis Ababa University
  • Tigist Solomon Negele Borena Zonal Hospital



Antiretroviral  therapy  has  led  to  a substantial  reduction  in  HIV associated  morbidity and  mortality. Efficacy  of  antiretroviral  treatment  in HIV/AIDS is showing inhibition of viral  replication and  reduction  of  viral  load  to  a  point  where  viral particles  are  undetectable  in  the  blood  of  infected individuals. Increasing recognition of medication adherence is a crucial factor in treatment outcomes.  This has led to the realization that HIV/AIDS is a  chronic  illness  and  hence the  quality of  life  of  PLWHA  needs  to  be  enhanced. The maintenance of viral suppression requires maximum adherence (at least 95%) to ART.


The objective of this review was to assess the recent literatures regarding interventions to improve antiretroviral medication adherence; to know factors affecting adherence, strategies to measure adherence to ART by reviewing research works done recently (2008-2013) on intervention to improve ARV adherence (adherence improving tools and strategies).


This literature review was obtained from electronic search on pubmed, AIDS LINES, MEDILINE, PyschInfo and also search was conducted on individual journals and manuals.


Adherence to ART is closely tied to virologic, immunologic, and clinical outcomes. Improving adherence requires collaborating with the patient in an effort to understand and ameliorate individual impediments to adherence, generally by establishing dedicated time with every patient to educate, plan for adherence, and maintain support and collaboration throughout the course of treatment.


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Author Biographies

Tesfaye Dalalo Gabriel, Addis Ababa University
Depatment of Pharmaceutics and Social Pharmacy, Lecturer
Tigist Solomon, Negele Borena Zonal Hospital
Hospital Pharmacist
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How to Cite
Gabriel, T., & Solomon, T. (2014). INTERVENTIONS TO IMPROVE ADHERENCE TO ANTIRETROVIRAL MEDICATIONS. Journal of Drug Delivery and Therapeutics, 4(6), 23-32.