ENVIRONMENTAL RESPONSIVE HYDROGELS: A NOVEL APPROACH IN DRUG DELIVERY SYSTEM

  • Anish Kumar Gupta Micro Labs ltd, Baddi, Himachal Pradesh, INDIA

Abstract

Hydrogels are three dimensional crosslinked hydrophilic polymeric networks which has the capability to imbibe water or biological fluids. Environmentally responsive hydrogels have the ability to respond to change in their external environment. They can exhibit dramatic changes in their swelling behaviour, network structure, permeability and mechanical strength in response to change in pH or ionic strength of the surrounding fluid or temperature. Other hydrogels have the ability to respond to applied electric or magnetic field or to change in concentration of glucose. Environmental responsive hydrogels for drug delivery application also requires biocompatibility. The chemical structure of the polymer may also affect the swelling ratio of hydrogels. Hydrogels containing hydrophilic groups swell to a higher degree compared to those containing hydrophobic groups. Swelling of environmentally responsive hydrogels can be affected by changes in the temperature of the swelling media, ionic strength and pH

Downloads

Download data is not yet available.

Author Biography

Anish Kumar Gupta, Micro Labs ltd, Baddi, Himachal Pradesh, INDIA
pharma
Statistics
276 Views | 299 Downloads
How to Cite
1.
Gupta A. ENVIRONMENTAL RESPONSIVE HYDROGELS: A NOVEL APPROACH IN DRUG DELIVERY SYSTEM. JDDT [Internet]. 20Jan.2012 [cited 27Nov.2021];2(1). Available from: http://jddtonline.info/index.php/jddt/article/view/87