EXTRACTION AND EVALUATION OF ISAPGHULA SEED POLYMER AS PHARMACEUTICAL EXCIPIENT

  • Praveen Kumar Nagar Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University Yamuna Expressway, Greater Noida, Gautam Buddh Nagar, India.
  • Parvez Nayyar Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University Yamuna Expressway, Greater Noida, Gautam Buddh Nagar, India.
  • Pramod Kumar Sharma Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University Yamuna Expressway, Greater Noida, Gautam Buddh Nagar, India.

Abstract

Aim of study. Present study includes extraction and characterization the isapghula (Plantago Ovata) seed polymer as pharmaceutical excipients.

Material and methods: By using water based extraction by heating mental isapghula seed polymer was obtained. For characterization of the extracted isapghula seed polymer phyto chemical screening was done and micromeritic properties, flow behavior, Solid forming capacity of polymer was also evaluated.

Results: The result predicts that extracted isapghula seed polymer was soluble in warm water while insoluble in cold water and in organic solvents. It was also exhibited that extracted isapghula seed polymer had good flow properties. pH was found 7.3, this showed that can be used in dosage form without any irritation. Results also showed that this polymer can be used to tablets binder.

Conclusions: From the results it was concluded that evaluated parameters showed that isapghula derived seed polymer can be used as pharmaceutical excipient to prepare solid as well as semisolid dosage form.

Key words: Isapghula seed polymer, extraction, characterization, natural polymer, pharmaceutical excipients.

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1.
Nagar P, Nayyar P, Sharma P. EXTRACTION AND EVALUATION OF ISAPGHULA SEED POLYMER AS PHARMACEUTICAL EXCIPIENT. JDDT [Internet]. 15May2014 [cited 4Dec.2021];4(3):122-4. Available from: http://jddtonline.info/index.php/jddt/article/view/856