DEVELOPMENT OF NEWER CONDUCTOMETRIC METHOD FOR ESTIMATION OF TELMISARTAN IN PURE AND FORMULATION

  • C M Jamkhandi Tatyasaheb Kore College of Pharmacy, Warananagar, Dist: Kolhapur, 416113, Maharashtra State, India.
  • Snehal R Salunkhe Tatyasaheb Kore College of Pharmacy, Warananagar, Dist: Kolhapur, 416113, Maharashtra State, India.
  • J I Disouza Tatyasaheb Kore College of Pharmacy, Warananagar, Dist: Kolhapur, 416113, Maharashtra State, India.
  • D A Bhagwat Bharati Vidyapeeth College of Pharmacy Kolhapur, Dist: Kolhapur, 416012, Maharashtra State, India
  • Charulata P Kuchekar Tatyasaheb Kore College of Pharmacy, Warananagar, Dist: Kolhapur, 416113, Maharashtra State, India.

Abstract

Objective of the present study is to develop simple, easily accessible, economic, newer conductometric method of estimation for Telmisartan.

Telmisartan is weak acid due to presence of acidic functional group which can be estimated by conductometric method in alcoholic media.  The developed method was validated according to ICH guidelines for parameters like accuracy, precision, specificity, ruggedness, robustness and percentage recovery.

Results: The Relative Standard Deviation was 0.701677; recovery was 98-100%. Tablet formulations were used as sample for estimation and the results are found to be well within the specified limit.

Conclusion: Therefore developed method can used for estimation of Telmisatan in pure or in formulations.

Key words: Conductometry, Telmisartan, Estimation, Weak acid.

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Jamkhandi C, Salunkhe S, Disouza J, Bhagwat D, Kuchekar C. DEVELOPMENT OF NEWER CONDUCTOMETRIC METHOD FOR ESTIMATION OF TELMISARTAN IN PURE AND FORMULATION. JDDT [Internet]. 15May2014 [cited 4Dec.2021];4(3):110-2. Available from: http://jddtonline.info/index.php/jddt/article/view/847