Profile of bioactive compounds in Rosmarinus officinalis
Plant Based Natural Products (PBNPs) have contributed to the development of drugs for diverse indications. Worldwide interest in use of PBNPs has been growing, and its beneficial effects being rediscovered for the development of drug leads. Literature survey on indigenous traditional knowledge bestows ethnopharmacological potentials of PBNPs, has inspired research in drug design and discovery; PBNPs provide a baseline for the development of novel drug leads against various pharmacological targets. Reports indicate that rosemary essential oil (ROEO) extracts show biological bioactivities such as hepatoprotective, antifungal, insecticide, antioxidant and antibacterial. However, their application is limited because of their odor, color and taste. Phytochemical screening indicates the presence of phenol, flavonoids, tannins, alkaloids, carbohydrates, proteins, glycosides, saponins, coumarins, terpenoids, quinones, steroids. Owing to widespread applications of phyto-compounds in ROEO - GCMS was performed. GCMS analysis detected the presence of 22 compounds (α-Pinene, Camphene, β-Myrcene, α-Terpinine, p-Cymene, trans-3-Caren-2-ol, 1,8-Cineole, γ-Terpinene, α-Terpinolene, Linalool, Isopulegol, Eucalyptol, Terpinen-4-ol, 2-Naphthalenol, (-)-Myrtenol, Verbenone, Terpine, α-Copaene, β-Caryophyllene, γ-Cadinene, Caryophyllene oxide) of which 6 compounds (α-Pinene, p-Cymene, Isopulegol, Eucalyptol, 2-Naphthalenol, Terpine) were in abundant. These compounds have been prospected for their molecular and biological properties in the present study.
Keywords: Rosmarinus officinalis; Rosemary Essential Oils (ROEO); GCMS; Bioprospecting; PBNPs
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