Nano Sponges: A Novel Approach for Targeted Drug Delivery Systems

  • K. Muni Raja Lakshmi Department Pharmaceutics, Sri Venkateswara University, Tirupati, Andhra Pradesh, India
  • CH. Suma Shree Department Pharmaceutics, Sri Venkateswara University, Tirupati, Andhra Pradesh, India
  • N. Lakshmi Priya Department Pharmaceutics, Sri Venkateswara University, Tirupati, Andhra Pradesh, India

Abstract

Targeted drug delivery system is a unique type of medication conveyance framework where the pharmacologically dynamic specialists mainly focused on its site activity and not to the non-focused on organs, tissues or cells. Nano sponges are such sort of compelling pharmaceutical transporters, which take care of issues like harmfulness and helpless bioavailability such as they can stack both hydrophilic and hydrophobic medicines. Various classifications of medications can stack into Nano sponge for focused medication conveyance. This targeted drug delivery system is one of the most encouraging methodologies in the existence of science. Nano sponges are little in size with a three-dimensional organization and nanometric depression. Nano sponges are exceptionally permeable and have the extraordinary capacity to ensure dynamic particles and offer programmable delivery. This Review article explains the overall presentation of nano sponges a grouping of nano sponge trademark highlights of nano sponges their points of interest inconveniences, and synthetic compounds utilized in their planning, arrangement of technical factors influencing on the preparation component activities and assessment boundaries with some particular applications. 


Keywords: Nano sponges; Targeted drug delivery; Solubility Enhancement; controlled drug delivery.

Keywords: Nano sponges, Targeted drug delivery, Solubility Enhancement, controlled drug delivery

Downloads

Download data is not yet available.

Author Biographies

K. Muni Raja Lakshmi, Department Pharmaceutics, Sri Venkateswara University, Tirupati, Andhra Pradesh, India

Department Pharmaceutics, Sri Venkateswara University, Tirupati, Andhra Pradesh, India

CH. Suma Shree, Department Pharmaceutics, Sri Venkateswara University, Tirupati, Andhra Pradesh, India

Department Pharmaceutics, Sri Venkateswara University, Tirupati, Andhra Pradesh, India

N. Lakshmi Priya, Department Pharmaceutics, Sri Venkateswara University, Tirupati, Andhra Pradesh, India

Department Pharmaceutics, Sri Venkateswara University, Tirupati, Andhra Pradesh, India

References

[1] Bhatia S. Nano sponges Types, Classification, Characterization, Fabrication Methods and Drug Delivery Applications. Natural Polymer Drug Delivery Systems, Springer International Publishing Switzerland, 2016.
[2] Thakre AR, Gholse YN, Kasliwal RH. Nano sponges: a novel approach of drug delivery system. J Med Pharm Allied Sci 2016; 78:103-111.
[3] Dhavala PB, Kumar VS. An Interesting Nano sponges as a Nanocarrier for Novel drug delivery: A Review, Int J of Pham and Med Res. 2017; 5(2).
[4] Khan KA, Bhargav E, reddy KR, Sowmya C. Nano sponges: A New Approach for Drug Targeting. Int. J pharm. pharm. res. 2016; 7(3):381-396.
[5] Majeed A, Khan NA, Ocular in situ gel: An overview. Journal of Drug Delivery and Therapeutics, 2019; 9(1):337-347. https://doi.org/10.22270/jddt.v9i1.2231.
[6] Suchita G. Waghmare, Rasika R. Nikhade, Dr. Satish and B. Kosalge. Nanosponges:a novel approach for controlled release drug delivery system.InternationalJournal of Pharmacy and Pharmaceutical research,2017; 9(3):101-11 .
[7] Shende, P.; Chaphalkar, R.; Deshmukh, K.; Gaud, R.S. Physicochemical Investigation of Engineered Nanosuspensions Containing Model Drug, Lansoprazole. J. Dispers. Sci. Technol. 2016; (37):504–511.
[8] Jyoti P, Tulsi B, Popin K, Chetna B. An Innovative Advancement for Targeted Drug Delivery: Nanosponges, Indo Global J Pharm Sci. 2016; 6(2):59-64.
[9] Arshad K, Khan A, Bhargav E, Reddy K and Sowmya C: Nanosponges: a new approach for drug targeting. International Journal of Advances in Pharmaceutical Research 2016; 7(3):381-96.
[10] Himanghshu Bhowmik, D. Nagasamy venkatesh, Anuttam Kuila Kammari Harish kumar international journal of pharmaceutical sciences 2018:10(4).
[11] Sabzi NE and Kiasat AR: β-Cyclodextrin based nanosponge as a biodegradable porous three-dimensional nanocatalyst in the one-pot synthesis of n-containing organic scaffolds. Catalysis Letters 2018: 1-11.
[12] Osmani RA, Kulkarni P, Manjunatha S, Gowda V, Hani U, Vaghela R and Bhosale R: Cyclodextrin Nanosponges in Drug Delivery and Nanotherapeutics. Environmental Nanotechnology 2018: 279-42.
[13] Bergal A, Elmas A, Akyüz G .A New Type and Effective Approach for Anti-Cancer Drug Delivery Application - A Nanosponge. Nano Res Appl ,I Med Pub journal; 2019; 3(1).
[14] Jyoti P, Tulsi B, Popin K, Chetna B. An Innovative Advancement for Targeted Drug Delivery: Nanosponges, Indo Global J Pharm Sci. 2016; 6(2):59-64.
[15] System Pawar AY, Naik AK, Jadhav KR, Nanosponges: A Novel Drug Delivery, Asian Journal of Pharmaceutics .2016; 10 (4).
[16]. Darandale SS, Shevalkar GB and Vavia PR: Effect of lipid composition in propofol formulations: decisive component in reducing the free propofol content and improving pharmacodynamic profiles. AAPS Pharm Sci Tech 2017; 18(2):441-50.
[17]. Kadian R. Nanoparticles: a promising drug delivery approach. Asian J Pharm Clin Res 2018; 11:30-5.
[18]. Pushpalatha R, Selvamuthukumar S, Kilimozhi D. Cross-linked, cyclodextrin-based nanosponges for curcumin delivery-physicochemical characterization, drug release, stability and cytotoxicity. J Drug Deliv Sci Technol 2018; 45-53.
Statistics
58 Views | 52 Downloads
How to Cite
1.
Muni Raja Lakshmi K, Suma Shree C, Lakshmi Priya N. Nano Sponges: A Novel Approach for Targeted Drug Delivery Systems. JDDT [Internet]. 15Mar.2021 [cited 20Apr.2021];11(2):247-52. Available from: http://jddtonline.info/index.php/jddt/article/view/4612