Dietary Patterns and Oxidative Stress in a Population of Women with Breast Cancer in the North-Western Regions of Algeria (Saida and El-Bayadh)

  • Noureddine Halla Laboratory of Biotoxicology, Pharmacognosy and Biological recovery of plants, Department of Biology, Faculty of Sciences, University of Saida - Dr. Moulay Tahar, Saida, 20000, Algeria
  • Kebir Boucherit Antibiotics Antifungal Laboratory, Physical Chemistry, Synthesis and Biological Activity (LAPSAB), Department of Biology, Faculty of Sciences, University of Tlemcen, BP 119, Tlemcen, 13000, Algeria
  • Kadda Hachem Laboratory of Biotoxicology, Pharmacognosy and Biological recovery of plants, Department of Biology, Faculty of Sciences, University of Saida - Dr. Moulay Tahar, Saida, 20000, Algeria
  • Amouria Asmouni Laboratory of Biotoxicology, Pharmacognosy and Biological recovery of plants, Department of Biology, Faculty of Sciences, University of Saida - Dr. Moulay Tahar, Saida, 20000, Algeria
  • Hanane Derrab Laboratory of Biotoxicology, Pharmacognosy and Biological recovery of plants, Department of Biology, Faculty of Sciences, University of Saida - Dr. Moulay Tahar, Saida, 20000, Algeria
  • Zahia Boucherit-Otmani Antibiotics Antifungal Laboratory, Physical Chemistry, Synthesis and Biological Activity (LAPSAB), Department of Biology, Faculty of Sciences, University of Tlemcen, BP 119, Tlemcen, 13000, Algeria

Abstract

Objective: The aim of this work is the study of risk factors for breast cancer in a population of women in the north-western regions of Algeria (Saida and El-Bayadh)


Methodology: A case-control study was carried out on 40 women including 20 cancerous women and 20 control women, in order to determine the dietary patterns and general characteristics of the population studied and to compare the hematological and biochemical parameters, and markers of oxidative/antioxidant status between control women and breast cancer women.


Results: The results obtained show that there is no significant difference in the average age however the body mass index was significantly increased in cancer women, revealing overweight (p <0.05), compared to control women. The marital status of the target population is predominantly a married woman status and the level of education shows a relatively low level in breast cancer cases compared to women controls. The illiteracy rate is exceptionally high in cancer women compared to controls (35% versus 20%). In addition, the levels of glucose, creatinine, HDL and ALAT are similar between the two groups of women. The contents of urea, cholesterol, triglyceride, LDL, ASAT, malondialdehyde and uric acid are significantly increased in women with breast cancer compared to women controls. But the vitamin C content is significantly reduced in cancer women compared to control women.


Conclusion: We conclude from this study that there is an association between breast cancer and lipid alteration, oxidative stress, age, increase in BMI, socio-demographic data, professional situation, age, means of menstruation and menopause, and ultimately the lifestyle. All these factors are risk factors for breast cancer in the region of Saida and El-Bayadh.


Keywords: Breast Cancer, Risk Factors, Dietary Patterns, Oxidative Stress.

Keywords: Breast Cancer, Risk Factors, Dietary Patterns, Oxidative Stress

Downloads

Download data is not yet available.

Author Biographies

Noureddine Halla, Laboratory of Biotoxicology, Pharmacognosy and Biological recovery of plants, Department of Biology, Faculty of Sciences, University of Saida - Dr. Moulay Tahar, Saida, 20000, Algeria

Laboratory of Biotoxicology, Pharmacognosy and Biological recovery of plants, Department of Biology, Faculty of Sciences, University of Saida - Dr. Moulay Tahar, Saida, 20000, Algeria

Kebir Boucherit, Antibiotics Antifungal Laboratory, Physical Chemistry, Synthesis and Biological Activity (LAPSAB), Department of Biology, Faculty of Sciences, University of Tlemcen, BP 119, Tlemcen, 13000, Algeria

Antibiotics Antifungal Laboratory, Physical Chemistry, Synthesis and Biological Activity (LAPSAB), Department of Biology, Faculty of Sciences, University of Tlemcen, BP 119, Tlemcen, 13000, Algeria

Kadda Hachem, Laboratory of Biotoxicology, Pharmacognosy and Biological recovery of plants, Department of Biology, Faculty of Sciences, University of Saida - Dr. Moulay Tahar, Saida, 20000, Algeria

Laboratory of Biotoxicology, Pharmacognosy and Biological recovery of plants, Department of Biology, Faculty of Sciences, University of Saida - Dr. Moulay Tahar, Saida, 20000, Algeria

Amouria Asmouni, Laboratory of Biotoxicology, Pharmacognosy and Biological recovery of plants, Department of Biology, Faculty of Sciences, University of Saida - Dr. Moulay Tahar, Saida, 20000, Algeria

Laboratory of Biotoxicology, Pharmacognosy and Biological recovery of plants, Department of Biology, Faculty of Sciences, University of Saida - Dr. Moulay Tahar, Saida, 20000, Algeria

Hanane Derrab, Laboratory of Biotoxicology, Pharmacognosy and Biological recovery of plants, Department of Biology, Faculty of Sciences, University of Saida - Dr. Moulay Tahar, Saida, 20000, Algeria

Laboratory of Biotoxicology, Pharmacognosy and Biological recovery of plants, Department of Biology, Faculty of Sciences, University of Saida - Dr. Moulay Tahar, Saida, 20000, Algeria

Zahia Boucherit-Otmani, Antibiotics Antifungal Laboratory, Physical Chemistry, Synthesis and Biological Activity (LAPSAB), Department of Biology, Faculty of Sciences, University of Tlemcen, BP 119, Tlemcen, 13000, Algeria

Antibiotics Antifungal Laboratory, Physical Chemistry, Synthesis and Biological Activity (LAPSAB), Department of Biology, Faculty of Sciences, University of Tlemcen, BP 119, Tlemcen, 13000, Algeria

References

1. ALGÉRIE PRESSE SERVICE; 2019. Available at : http://www.aps.dz/sante-science-technologie/96199-cancer-du-sein-le-depistage-precoce-de-nouveau-preconise. Accessed July 23, 2020.
2. Henaoui L, Meguenni K; Facteurs de risque du cancer du sein-Étude cas-témoins Wilaya de Tlemcen, 2015–2017. Rev Epidémiol Santé Publique 2020; 68:S139.
3. Cespedes E, Hu FB; Dietary patterns: from nutritional epidemio-logic analysis to national guidelines. Am J Clin Nutr 2015; 101:899–900.
4. Lee JD, Cai Q, Shu XO, Nechuta SJ; The role of biomarkers of oxidative stress in breast cancer risk and prognosis: A systematic review of the epidemiologic literature. J Womens Health 2017; 26(5):467-482.
5. Badid N, Ahmed FZB, Merzouk H, Belbraouet S, Mokhtari N, Merzouk SA, Narce M; Oxidant/antioxidant status, lipids and hormonal profile in overweight women with breast cancer. Pathol Oncol Res 2010; 16(2):159-167.
6. Jagota SK, Dani HM; A new colorimetric technique for the estimation of vitamin C using Folin phenol reagent. Anal Biochem 1982; 127(1):178-182.
7. Beauvieux MC, Gin H, Peuchant E; Le stress oxydant et ses marqueurs biologiques. Cah. de Nutr et de Diét. 2002; 37(1):45-51.
8. Vibet S, Goupille C, Bougnoux P, Steghens JP, Goré J, Mahéo K; Sensitization by docosahexaenoic acid (DHA) of breast cancer cells to anthracyclines through loss of glutathione peroxidase (GPx1) response. Free Radic Biol Med 2008; 44(7):1483-1491.
9. Lean M; Diagnostic criteria and assessment of obesity in adults. Adv Nutr Dietetics in Obesity 2018; 24.
10. Harvie MN, Bokhari S, Shenton A, Ashcroft L, Evans G, Swindell R, Howell A; Adult weight gain and central obesity in women with and without a family history of breast cancer: a case control study. Fam Cancer 2007; 6(3):287-294.
11. Reinehr T, Roth CL; Is there a causal relationship between obesity and puberty?. Lancet Child Adolesc Health 2019; 3(1):44-54.
12. Engmann NJ, Golmakani MK, Miglioretti DL, Sprague BL, Kerlikowske K; Population-attributable risk proportion of clinical risk factors for breast cancer. JAMA Oncol 2017; 3(9):1228-1236.
13. Kaffashian F, Godward S, Davies T, Solomon L, McCann J, Duffy SW; Socioeconomic effects on breast cancer survival: proportion attributable to stage and morphology. Br J cancer 2003; 89(9):1693-1696.
14. Robert SA, Strombom I, Trentham-Dietz A, Hampton JM, McElroy JA, Newcomb PA, Remington PL; Socioeconomic risk factors for breast cancer: distinguishing individual-and community-level effects. Epidemiol 2004; 442-450.
15. Daniels N, Kennedy B, Kawachi I; Justice is good for our health. Boston Rev 2000; 25(1):4-9.
16. Franklin B, Jones A, Love D, Puckett S, Macklin J, White-Means S; Exploring mediators of food insecurity and obesity: a review of recent literature. J community health 2012; 37(1):253-264.
17. Seligman HK, Schillinger D; Hunger and socioeconomic disparities in chronic disease. N Engl J Med 2010; 363(1):6-9.
18. Murthy VH; Food insecurity: a public health issue. Public Health Rep (1974-) 2016; 131(5):655-657.
19. Bruening M, Dinour LM, Chavez JBR; Food insecurity and emotional health in the USA: a systematic narrative review of longitudinal research. Public Health Nutr 2017; 20(17):3200-3208
20. Kohler BA, Sherman RL, Howlader N, Jemal A, Ryerson AB, Henry KA, Henley SJ; Annual report to the nation on the status of cancer, 1975-2011, featuring incidence of breast cancer subtypes by race/ethnicity, poverty, and state. J Nat Cancer Inst 2015; 107(6).
21. Dean LT, Gehlert S, Neuhouser ML, Oh A, Zanetti K, Goodman M, Schmitz KH; Social factors matter in cancer risk and survivorship. Cancer Causes Control 2018; 29(7):611-618.
22. Feinglass J, Rydzewski N, Yang A; The socioeconomic gradient in all-cause mortality for women with breast cancer: findings from the 1998 to 2006 National Cancer Data Base with follow-up through 2011. Ann Epidemiol 2015; 25(8):549-555.
23. Coughlin SS; Social determinants of breast cancer risk, stage, and survival. Breast Cancer Res Treat 2019; 1-12.
24. Nichols HB, Schoemaker MJ, Cai J, Xu J, Wright LB, Brook MN, Blot WJ; Breast cancer risk after recent childbirth: a pooled analysis of 15 prospective studies. Ann Intern Med 2019; 170(1):22-30.
25. Zucchetti BM, Peccatori FA, Codacci-Pisanelli G; Pregnancy and Lactation: Risk or Protective Factors for Breast Cancer?. In: Diseases of the Breast during Pregnancy and Lactation. Springer, Cham.; 2020. p. 195-197.
26. Akram M, Iqbal M, Daniyal M, Khan AU; Awareness and current knowledge of breast cancer. Biol Res 2017; 50(1):33.
27. Guo W, Fensom GK, Reeves GK, Key TJ; Physical activity and breast cancer risk: results from the UK Biobank prospective cohort. Br J Cancer 2020; 122(5):726-732.
28. Friedenreich CM, Orenstein MR; Physical activity and cancer prevention: etiologic evidence and biological mechanisms. J Nutr 2002;132(11):3456S-3464S.
29. Lagerros YT, Hsieh SF, Hsieh CC; Physical activity in adolescence and young adulthood and breast cancer risk: a quantitative review. Eur J Cancer Prev 2004; 13(1):5-12.
30. Mohseny M, Amanpour F, Mosavi-Jarrahi A, Jafari H, Moradi-Joo M, Monfared ED; Application of Cox and Parametric Survival Models to Assess Social Determinants of Health Affecting Three-Year Survival of Breast Cancer Patients. Asian Pac J Cancer Prev 2016; 17(sup3):311-316.
31. Singh GK, Daus GP, Allender M, Ramey CT, Martin EK, Perry C, Vedamuthu IP; Social determinants of health in the United States: addressing major health inequality trends for the nation, 1935-2016. Int J MCH AIDS 2017; 6(2):139.
32. Noonan AS, Velasco-Mondragon HE, Wagner FA; Improving the health of African Americans in the USA: an overdue opportunity for social justice. Public health reviews 2016; 37(1):1-20.
33. Grosso G, Bella F, Godos J, Sciacca S, Del Rio D, Ray S, Giovannucci EL; Possible role of diet in cancer: systematic review and multiple meta-analyses of dietary patterns, lifestyle factors, and cancer risk. Nutr Rev 2017; 75(6):405-419.
34. Turati F, Carioli G, Bravi F, Ferraroni M, Serraino D, Montella M, La Vecchia C; Mediterranean diet and breast cancer risk. Nutrients 2018; 10(3):326.
35. Playdon MC, Ziegler RG, Sampson JN, Stolzenberg-Solomon R, Thompson HJ, Irwin ML, Moore SC; Nutritional metabolomics and breast cancer risk in a prospective study. Am J Clin Nutr 2017; 106(2):637-649.
36. David RM, Gooderham NJ; Ethanol potentiates the genotoxicity of the food-derived mammary carcinogen PhIP in human estrogen receptor-positive mammary cells: mechanistic support for lifestyle factors (cooked red meat and ethanol) associated with mammary cancer. Arch Toxicol 2018; 92(4):1639-1655.
37. Anstey EH, Shoemaker ML, Barrera CM, O’Neil ME, Verma AB, Holman DM; Breastfeeding and breast cancer risk reduction: implications for black mothers. Am J Prev Med 2017; 53(3):S40-S46.
38. Li X, Tang H, Wang J, Xie X, Liu P, Kong Y, Xie X; The effect of preoperative serum triglycerides and high-density lipoprotein-cholesterol levels on the prognosis of breast cancer. Breast 2017; 32:1-6.
39. Olivecrona G; Role of lipoprotein lipase in lipid metabolism. Curr Opin Lipidol 2016; 27(3):233-241.
40. Gurer-Orhan H, Ince E, Konyar D, Saso L, Suzen S; The role of oxidative stress modulators in breast cancer. Curr Med Chem 2018; 25(33):4084-4101.
41. Hecht F, Pessoa CF, Gentile LB, Rosenthal D, Carvalho DP, Fortunato RS; The role of oxidative stress on breast cancer development and therapy. Tumor Biol 2016; 37(4):4281-4291.
Statistics
49 Views | 34 Downloads
How to Cite
1.
Halla N, Boucherit K, Hachem K, Asmouni A, Derrab H, Boucherit-Otmani Z. Dietary Patterns and Oxidative Stress in a Population of Women with Breast Cancer in the North-Western Regions of Algeria (Saida and El-Bayadh). JDDT [Internet]. 15Nov.2020 [cited 26Nov.2020];10(6):24-0. Available from: http://jddtonline.info/index.php/jddt/article/view/4543