Improving Bioavailability of Phytochemicals through Niosomes
The role of nanotechnology in different sectors is increasing and improving day by day. The nanovectors or nanovehicles play a very major role in transporting essential components into the body across barriers, such as skin, intestine, blood-brain barrier, etc., which is a very essential part of pharmacology. Niosomes are one such vehicle of nano size, which can effectively improve the delivering properties of therapeutically and cosmeceutically important compounds. This short review examines different research that has been carried out in the last two decades involving niosomes to improve the bioavailability of pharmaceutically important phytochemical compounds.
Keywords: Niosomes, Phytochemicals, Bioavailability, Drug delivery
2. Marianecci C, Di Marzio L, Rinaldi F, Celia C, Paolino D, Alhaique F, et al. Niosomes from 80s to present: the state of the art. Adv Colloid Interface Sci. 2014 Mar; 205:187–206.
3. Khazaeli P, Pardakhty A, Shoorabi H. Caffeine-Loaded Niosomes: Characterization and in Vitro Release Studies. Drug Deliv. 2007 Jan 1; 14(7):447–52.
4. Manosroi A, Chutoprapat R, Sato Y, Miyamoto K, Hsueh K, Abe M, et al. Antioxidant activities and skin hydration effects of rice bran bioactive compounds entrapped in Niosomes. J Nanosci Nanotechnol. 2011; 11(3):2269–77.
5. Kamble B, Talreja S, Gupta A, Patil D, Pathak D, Moothedath I, et al. Development and biological evaluation of Gymnema sylvestre extract-loaded nonionic surfactant-based niosomes. Nanomedicine (Lond). 2013 Aug; 8(8):1295–305.
6. Jin Y, Wen J, Garg S, Liu D, Zhou Y, Teng L, et al. Development of a novel niosomal system for oral delivery of Ginkgo biloba extract. Int J Nanomedicine. 2013/01/24. 2013; 8:421–30.
7. Xu Y-Q, Chen W-R, Tsosie JK, Xie X, Li P, Wan J-B, et al. Niosome Encapsulation of Curcumin: Characterization and Cytotoxic Effect on Ovarian Cancer Cells. Gref R, editor. J Nanomater. 2016; 2016:6365295.
8. Chinembiri TN, Gerber M, du Plessis LH, du Preez JL, Hamman JH, du Plessis J. Topical Delivery of Withania somnifera Crude Extracts in Niosomes and Solid Lipid Nanoparticles. Pharmacogn Mag. 2017 Oct; 13(Suppl 3):S663–71.
9. Raeiszadeh M, Pardakhty A, Sharififar F, Mehrabani M, Nejat-Mehrab-Kermani H, Mehrabani M. Phytoniosome: a Novel Drug Delivery for Myrtle Extract. Iran J Pharm Res IJPR. 2018; 17(3):804–17.
10. Charoensup R, Duangyod T, Palanuvej C, Ruangrungsi N. Pharmacognostic Specifications and Lawsone Content of Lawsonia inermis Leaves. Pharmacognosy Res. 2017; 9(1):60–4.
11. Barani M, Mirzaei M, Torkzadeh-Mahani M, Nematollahi MH. Lawsone-loaded Niosome and its antitumor activity in MCF-7 breast Cancer cell line: a Nano-herbal treatment for Cancer. DARU J Pharm Sci. 2018; 26(1):11–7.
12. Mohamad EA, Fahmy HM. Niosomes and liposomes as promising carriers for dermal delivery of Annona squamosa extract. Brazilian J Pharm Sci. 2020; 56.
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