Prescribing Pattern of Drugs Used in Chronic Liver Disease with Co Morbid Conditions and Assessment of Severity using MELD Score: A Prospective Observational Study

  • Samreen Huma Pharm D., Department of Pharmacy Practice, Mesco College of Pharmacy, Hyderabad, Telangana, India
  • Omer Nishat Fatima Pharm D., Department of Pharmacy Practice, Mesco College of Pharmacy, Hyderabad, Telangana, India
  • Ishrath Ayesha Pharm D., Department of Pharmacy Practice, Mesco College of Pharmacy, Hyderabad, Telangana, India
  • Jamal Mohammed Moiz Pharm D., Department of Pharmacy Practice, Mesco College of Pharmacy, Hyderabad, Telangana, India
  • Shareef Mohammed Mohiuddin Assistant Professor, Department of Pharmacy Practice, Mesco College of Pharmacy, Hyderabad, Telangana, India

Abstract

Objectives: To study the prescribing pattern of drugs & its use in the treatment of CLD & assess the pattern of co-morbidities associated with CLD. To Study the mortality rate of the patient using MELD score at a department of general medicine at Osmania general Hospital to produce a result which would aid better rational drug use and improve quality of life.


Methodology: A Prospective, observational study was carried out at OGH for a period of 6 months in 100 old patients. Population of either sex or ≥ 18 years of age were included.


Conclusion: There is a considerable scope for improving prescribing pattern in CLD by minimizing the use, reduction of doses of drugs to reduce the consequence of hepatotoxicity and Antibiotic Resistance. The prognostic impact of individual comorbidities, on the other hand, may point to areas where cirrhosis and comorbid diseases interact. Studies of individual comorbidities may therefore improve our understanding of the pathophysiology of cirrhosis. MELD showed that the subjects were less likely to get a Liver transplant.


Keywords: Chronic liver disease (CLD), Model for end stage liver disease (MELD), Diabetes Mellitus (DM), hypertension (HTN)

Keywords: Chronic liver disease (CLD), Model for end stage liver disease (MELD), Diabetes Mellitus (DM), hypertension (HTN)

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Author Biographies

Samreen Huma, Pharm D., Department of Pharmacy Practice, Mesco College of Pharmacy, Hyderabad, Telangana, India

Pharm D., Department of Pharmacy Practice, Mesco College of Pharmacy, Hyderabad, Telangana, India

Omer Nishat Fatima, Pharm D., Department of Pharmacy Practice, Mesco College of Pharmacy, Hyderabad, Telangana, India

Pharm D., Department of Pharmacy Practice, Mesco College of Pharmacy, Hyderabad, Telangana, India

Ishrath Ayesha, Pharm D., Department of Pharmacy Practice, Mesco College of Pharmacy, Hyderabad, Telangana, India

Pharm D., Department of Pharmacy Practice, Mesco College of Pharmacy, Hyderabad, Telangana, India

Jamal Mohammed Moiz, Pharm D., Department of Pharmacy Practice, Mesco College of Pharmacy, Hyderabad, Telangana, India

Pharm D., Department of Pharmacy Practice, Mesco College of Pharmacy, Hyderabad, Telangana, India

Shareef Mohammed Mohiuddin, Assistant Professor, Department of Pharmacy Practice, Mesco College of Pharmacy, Hyderabad, Telangana, India

Assistant Professor, Department of Pharmacy Practice, Mesco College of Pharmacy, Hyderabad, Telangana, India

References

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1.
Huma S, Fatima ON, Ayesha I, Moiz JM, Mohiuddin SM. Prescribing Pattern of Drugs Used in Chronic Liver Disease with Co Morbid Conditions and Assessment of Severity using MELD Score: A Prospective Observational Study. JDDT [Internet]. 15Oct.2020 [cited 21Oct.2020];10(5-s):19-4. Available from: http://jddtonline.info/index.php/jddt/article/view/4436