Creams: A Review on Classification, Preparation Methods, Evaluation and its Applications

  • Lalita Chauhan School of Pharmacy and Emerging Sciences, Baddi University of Emerging Sciences and Technology, Village Makhnumajra Baddi District Solan, Tehsil Nalagarh, H.P-173205
  • Shalini Gupta School of Pharmacy and Emerging Sciences, Baddi University of Emerging Sciences and Technology, Village Makhnumajra Baddi District Solan, Tehsil Nalagarh, H.P-173205

Abstract

Creams are considered an important part of cosmetic product as topical preparations from time immemorial due to their ease of application to the skin and also their removal. From cosmetic purposes, Pharmaceutical creams have a variety of applications such as cleansing, beautifying, altering appearance, moisturizing etc. to skin protection against bacterial, fungal infections as well as healing cuts, burns, wounds on the skin. These semi solid preparations are safe to use by the public and society. The human skin is easily vulnerable to injury but it has the capability to heal on its own. However, the natural healing process can take time and there is also risk of infection especially in the early stages of injury. In such cases, medicated creams can be applied to the site of injury to speed up the healing process as well as protect the wound from infection. In this review, we have focused on the use of topical drug delivery system i.e. pharmaceutical creams for wound healing with detailed discussion relating to the wound healing process, suitable methods of preparation of creams, their classification based on their function, their advantages and disadvantages, characteristics and the various types of creams, ingredients used in the formulation of creams and their various evaluation parameters.


Keywords: Creams, Skin, Topical drug delivery system, Wound healing

Keywords: Creams, Skin, Topical drug delivery system, Wound healing

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Author Biographies

Lalita Chauhan, School of Pharmacy and Emerging Sciences, Baddi University of Emerging Sciences and Technology, Village Makhnumajra Baddi District Solan, Tehsil Nalagarh, H.P-173205

School of Pharmacy and Emerging Sciences, Baddi University of Emerging Sciences and Technology, Village Makhnumajra Baddi District Solan, Tehsil Nalagarh, H.P-173205

Shalini Gupta, School of Pharmacy and Emerging Sciences, Baddi University of Emerging Sciences and Technology, Village Makhnumajra Baddi District Solan, Tehsil Nalagarh, H.P-173205

School of Pharmacy and Emerging Sciences, Baddi University of Emerging Sciences and Technology, Village Makhnumajra Baddi District Solan, Tehsil Nalagarh, H.P-173205

References

1. Shah RN, Methal BM, A Hand book of Cosmetics Page No.1
2. Myers D, Surfactant Science and Technology, VCH Publishers: 1992, Pp. 209‐247
3. Sahu T, Patel T , Sahu S, Gidwani B,“Skin Cream as Topical Drug Delivery System: A Review” Journal of Pharmaceutical and Biological Sciences, Published by Atom and Cell Publishers, ISSN: 2320-1924
4. James WD, Berger TG, and Elston DM, Andrews’ Diseases of the Skin: Clinical Dermatology. (10th ed.) 2006, Philadelphia; Elsevier Saunders: 2006, p. 1.
5. Ross and Wilson. Anatomy and Physiology in Health and Illness, 11e
6. Ansel HC, Popovich NG, Allen LV. Pharmaceutical dosage forms and drug delivery systems. Lippincott Williams & Wilkins; 1995.
7. Rai R, Poudyl AP, Das S, Pharmaceutical Creams and their use in wound healing: A Review, Journal of Drug Delivery and Therapeutics, 2019; 9(3-s): 907-912 http://dx.doi.org/10.22270/jddt.v9i3-s.3042
8. Sahu T, Patel T, Sahu S, Gidwani B, “Skin cream as Topical Drug Delivery System: A Review” Journal of Pharmaceutical and Biological Sciences, 2016; 4(5):149-154
9. Mohiuddin AK, “Skin Care Creams: Formulation and Use” American Journal of Dermatological Research and Reviews, 2019, 2:8
10. Chapter 11. Semi-solid dosage forms. In: Alekha Dash, Somnath Singh, Justin Tolman. Pharmaceutics: Basic Principles and Application to Pharmacy Practice, published by Academic Press, 2013 ISBN 0123868912, 9780123868916
11. Swarbrick J, Rubino JT, Rubino OP. Chapter 22. Coarse Dispersions. In: Remington: The Science and Practice of Pharmacy Volume 1, edited by David B. Troy, Paul Beringer, published by Lippincott Williams & Wilkins, 2006 ISBN 0781746736, 9780781746731
12. Jamshiya S, “Formulation and Evaluation of Herbal Skin Cream for Wound Healing” (Doctoral dissertation, RVS College of Pharmaceutical Sciences, Coimbatore
13. Rani S, Singh N ,Gautam SP, “Formulation, Evaluation Optimization and Evaluation of Dendricream for wound healing activity of Artemisia Indica” World journal of pharmacy and pharmaceutical sciences, 2016; 5(8):1483-1497.
14. Esimone CO, Ibezim EC, Chah KF, “Factors affecting wound healing” Journal of Pharma Allied Sciences, 2005; (1):294-299.
15. Avinash G, Priyanka B, “Wound healing potential of Indian medicinal plants” International Journal of Pharmacy Review & Res, 2013; 2:75-87.
16. Pal A, Soni M, Patidar K, “Formulation and evaluation of polyherbal cream” International Journal Pharmaceutical and Biological Archives, 2014; 5:67-71.
17. Patel RP, KamaniR, “Formulation Optimization and Evaluation of Mometazone Furoate Cream” Journal of Pharmacy Research, 2009; 10:1565-1569.
18. Aswal A, Kalra M, Rout A, “Preparation and evaluation of polyherbal cosmetic cream” Der Pharmacia Lettre, 2013; 5(1):838
19. Sherrow V, “For Appearance' Sake: The Historical Encyclopedia of Good Looks” Beauty, and Grooming, 1995; 4:238–39.
20. Jamshiya S, “Formulation and Evaluation of Herbal Skin Cream for Wound Healing” (Doctoral dissertation, RVS College of Pharmaceutical Sciences, Coimbatore).
21. Avinash G, Priyanka B, “Wound healing potential of Indian medicinal plants” International Journal of Pharmacy Review & Res, 2013;2:75-87.
22. Mittal A, Sardana S, “Herbal boon for wounds” International Journal of Pharmacy and Pharmaceutical Sciences, 2013; 5:1-12
23. Tiwari VK, “Burn wound: How it differs from other wounds?” Indian journal of plastic surgery: official publication of the Association of Plastic Surgeons of India. 2012 May; 45(2):364.
24. Sarabahi S, Tiwari VK, “Principles and practice of wound care’ JP Medical Ltd; 2012 May 15.
25. Kiran K, Asad M, “Wound healing activity of Sesamum indicum L seed and oil in rats”
26. James OM, Victoria IA, “Excision and incision wound healing potential of Saba florida (Benth) leaf extract in Rattusnovergicus” Inter J Pharm Biomed Res, 2010; 1(4):101-7
27. Saini S, Dhiman A, Nanda S, “Traditional Indian medicinal plants with potential wound healing activity: a review” International Journal of Pharmaceutical Sciences and Research, 2016; 7(5):1809
28. DiPietro LA, Burns AL, editors. Wound healing: methods and protocols. Springer Science & Business Media; 2003
29. Builders PF, Kabele-Toge B, Builders M, Chindo BA, Anwunobi PA, Isimi YC, “Wound healing potential of formulated extract from hibiscus sabdariffa calyx” Indian journal of pharmaceutical sciences, 2013; 75(1):45.
30. Biswas TK, Mukherjee B, “Plant medicines of Indian origin for wound healing activity: a review” The international journal of lower extremity wounds, 2003; 2(1):25-39.
31. Prasad V, Dorle AK, “Evaluation of ghee based formulation for wound healing activity” Journal of ethnopharmacology, 2006; 107(1):38-47.
32. Duke JA. Handbook of medicinal herbs. CRC press; 2002 Jun 27.
33. Govindarajan R, Vijayakumar M, Rao CV, Shirwaikar AN, Mehrotra S, Pushpangadan P, “Healing potential of Anogeissuslatifolia for dermal wounds in rats” Acta Pharm. 2004; 54(4):331-8
34. Kulkarni PH, “The Encyclopedia of Ayurveda” Sri Satguru publication, 2005; 1:288-9.
35. Oryan A, Mohammadalipour A, Moshiri A, Tabandeh MR, “Topical application of Aloe vera accelerated wound healing, modeling, and remodeling: an experimental study” Annals of plastic surgery, 2016; 77(1):37-46
36. Herro E, Jacob SE. Menthapiperita (peppermint). Dermatitis. 2010; 21(6):327-9.
37. Modarresi M, Farahpour MR, Baradaran B, “Topical application of Menthapiperita essential oil accelerates wound healing in infected mice model” Inflammopharmacology, 2018: 6:1-7.
38. Saidi M, Aouacheri O, Saka S, “Protective Effect of Curcuma Against Chromium Hepatotoxicity in Rats” Phytothérapie. 2019.
39. Luthra PM, Singh R, Chandra R. Therapeutic uses ofCurcuma longa (turmeric). Indian Journal of Clinical Biochemistry. 2001; 16(2):153-60
40. Shetty S, Udupa SL, Udupa AL, Vollala VR, “Wound healing activities of Bark Extract of Jatrophacurcas Linn in albino rats” Saudi Medical Journal, 2006; 27(10):1473-6
41. Bodeker G, Ryan T, Ong CK, “Traditional approaches to wound healing. Clinics in dermatology” 1999; 17(1):93-8.
42. Kwakman PH, Zaat SA, “Antibacterial components of honey” IUBMB life. 2012; 64(1):48-55
43. Parente LM, Júnior L, de Souza R, Tresvenzol LM, Vinaud MC, de Paula JR, Paulo NM, “Wound healing and anti-inflammatory effect in animal models of Calendula officinalis L. growing in Brazil” Evidence-based complementary and alternative medicine, 2012;
44. Preethi KC, Kuttan R, “Wound healing activity of flower extract of Calendula offlcinalis” Journal of basic and clinical physiology and pharmacology, 2009; 20(1):73-80
45. Prasad V, Dorle AK, “Evaluation of ghee based formulation for wound healing activity” Journal of ethnopharmacology, 2006; 107(1):38-47
46. World Health Organization. General guidelines for methodologies on research and evaluation of traditional medicine. Geneva: World Health Organization; 2000
47. Inpanya P, Faikrua A, Ounaroon A. Sittichokechaiwut A, and Viyoch J, Effects of the blended fibroin/aloe gel film on wound healing in streptozotocin-induced diabetic rats. Biomed Mater. 2012; 7:035008.
48. Tarameshloo M, Norouzian M, Zarein-Dolab S, Dadpay M, Mohsenifar J, and Gazor R, “Aloe vera gel and thyroid hormone cream may improve wound healing in Wistar rats” Anat Cell Biol, 2012; 45:170.
49. Atiba A, Nishimura M, Kakinuma S, Hiraoka T, Goryo M, Shimada Y, Ueno H, and UzukaY, “Aloevera oral administration accelerates acute radiation-delayed wound healing by stimulating transforming growth factor-b and fibroblast growth factor production’ Am J Surg, 2011; 201:809.
50. Eshghi F, Hosseinimehr SJ, Rahmani N, Khademloo M, Norozi MS, and Hojati O, “Effects of Aloe vera cream on posthemorrhoidectomy pain and wound healing: results of a randomized, blind, placebo-control study” J Altern Complement Med, 2010; 16:647.
51. Takzare N, Hosseini MJ, Hasanzadeh G, Mortazavi H, Takzare A, and Habibi P, “Influence of Aloe vera gel on dermal wound healing process in rat” Toxicol Mech Methods, 2009: 19:73
52. Upadhyay NK, Kumar R, Mandotra SK, Meena RN, Siddiqui MS, Sawhney RC, and Gupta A, “Safety and healing efficacy of Sea buckthorn (Hippophaerhamnoides L.) seed oil on burn wounds in rats” Food Chem Toxicol, 2009; 47:1146.
53. Gupta A, Kumar R, Pal K, Singh V, Banerjee PK, and Sawhney RC, “Influence of sea buckthorn (Hippophaerhamnoides L.) flavone on dermal wound healing in rats” Mol Cell Biochem, 2006; 290:193.
54. Hsiao C-Y, Hung C-Y, Tsai T-H, and Chak K-F, “A study of the wound healing mechanism of a traditional chinese medicine, Angelica sinensis, using a proteomic approach” Evid Based Complement Alternat Med, 2012: Article ID 467531.
55. Nayak BS, Pereira LMP, “Catharanthus roseus flower extract has wound-healing activity in Sprague Dawley rats” BMC Complement Alternat Med, 2006; 6:41.
56. Shenoy RR, Sudheendra AT, Nayak PG, Paul P, Kutty NG, and Rao CM, “Normal and delayed wound healing is improved by sesamol, an active constituent of Sesamum indicum (L.) in albino rats” J Ethnopharmacol, 2011; 133:608
57. Naeini AT, Miri R, Shafiei N, Tabandeh MR, Oryan A, and Nazifi S, “Effects of topical application of Calendula officinalis gel on collagen and hydroxyproline content of skin in rats” Comp Clin Pathol, 2012; 21:253.
58. Parente LML, Ju ´nior RSL, Tresvenzol LMF, Vinaud MC, de Paula JR, and Paulo NM, “Wound healing and anti-inflammatory effect in animal models of Calendula officinalis L. growing in Brazil” Evid Based Complement Alternat Med, 2012: 375671
59. Fronza M, Heinzmann B, Hamburger M, Laufer S, and Merfort I, “Determination of the wound healing effect of Calendula extracts using the scratch assay with 3T3 fibroblasts” J Ethnopharmacol, 2009; 10: 126.
60. Tiwari PC, Noor MA, Chand PK, Nagar K, Comparative Study of Wound Healing Activity of Soframycin and Honey in Excision Wound Model. National Library of Medicine, Pubmed. 2013.
61. Teran CG, Sura S, Cabandugama P, Berson C, “Silver nitrate ingestion: report of a case with an uneventful course and review of the literature” Clinics and practice, 2011; 1(3)
62. Maghsoudi H, Monshizadeh S, Mesgari M, “A comparative study of the burn wound healing properties of saline-soaked dressing and silver sulfadiazine in rats” Indian Journal of Surgery, 2011; 73(1):24-7
63. Bigliardi PL, Alsagoff SA, El-Kafrawi HY, Pyon JK, Wa CT, Villa MA, “Povidone iodine in wound healing: A review of current concepts and practices” International Journal of Surgery, 2017; 44:260-8.
64. Pal A, Soni M, Patidar K, “Formulation and evaluation of polyherbal cream” International Journal Pharmaceutical and Biological Archives, 2014; 5: 67-71
65. Aswal A, Kalra M, Rout A, “Preparation and evaluation of polyherbal cosmetic cream” Der Pharmacia Lettre, 2013; 5(1):838.
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Chauhan L, Gupta S. Creams: A Review on Classification, Preparation Methods, Evaluation and its Applications. JDDT [Internet]. 15Oct.2020 [cited 21Oct.2020];10(5-s):281-9. Available from: http://jddtonline.info/index.php/jddt/article/view/4430