A Review on Hair Growth Regulator

  • Manu Bharti Department of Pharmacology, School of Pharmaceutical Science, IFTM University, Moradabad, U.P., India
  • Alankar Shrivastav Department of Pharmacology, Pharmacy Academy, IFTM University, Moradabad, U.P., India
  • M. Abid Department of Pharmacology, School of Pharmaceutical Science, IFTM University, Moradabad, U.P., India
  • Najam Ali Khan Department of Pharmacology, School of Pharmaceutical Science, IFTM University, Moradabad, U.P., India

Abstract

This review presents an overview on plants identified to possess hair growth activity in various ethno-botanical studies and surveys of tradition medicinal plants. There are various causes for hair loss and the phenomenon is still not fully understood. The treatments offered include both natural or synthetic products to treat the condition of hair loss (alopecia), nonetheless natural products are continuously gaining popularity mainly due to their fewer side effects and better formulation strategies for natural product extracts. Plants have been widely used for hair growth promotion since ancient times as reported in Ayurveda, Chinese and Unani systems of medicine. This review covers information about different herbs and herbal formulation that are believed to be able to reduce the rate of hair loss and at the same time stimulate new hair growth. A focus is placed on their mechanism of action and the review also covers various isolated phytoconstituents possessing hair growth promoting effect.


Keywords: Alopecia, ayurveda, hair, herbal formulation.

Keywords: Alopecia, ayurveda, hair, herbal formulation

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Author Biographies

Manu Bharti, Department of Pharmacology, School of Pharmaceutical Science, IFTM University, Moradabad, U.P., India

Department of Pharmacology, School of Pharmaceutical Science, IFTM University, Moradabad, U.P., India

Alankar Shrivastav, Department of Pharmacology, Pharmacy Academy, IFTM University, Moradabad, U.P., India

Department of Pharmacology, Pharmacy Academy, IFTM University, Moradabad, U.P., India

M. Abid, Department of Pharmacology, School of Pharmaceutical Science, IFTM University, Moradabad, U.P., India

Department of Pharmacology, School of Pharmaceutical Science, IFTM University, Moradabad, U.P., India

Najam Ali Khan, Department of Pharmacology, School of Pharmaceutical Science, IFTM University, Moradabad, U.P., India

Department of Pharmacology, School of Pharmaceutical Science, IFTM University, Moradabad, U.P., India

References

[1] Andrew GM. The Control of Hair Growth: An Overview. J Inves Dermatol 1993; 10:523-27.
[2] Kumar N, Singh S, Manvi. Hair Growth Activity of Trichosanthes dioica R. Leaves. J Pharmacog Phytochem 2011; 3:30.
[3] Chase HB.Growth of the hair. Physiolog Rev 1954; 34:113-26.
[4] Venning VA, Dawber RPR. Patterned androgenetic alopecia in women. J Amer Acad Dermatol 1998; 18:1073-77.
[5] Kobayashi N, Suzuki R, Koide C, Suzuki T, Matsuda H, Kubo M. Effect of leaves of Ginkgo biloba on hair regrowth in C3H strain mice.Yakugaku Zasshi 1993; 113:718-24.
[6] Dry FW. The coat of the mouse. J Gene 1926; 16:287-340.
[7] Butler H, Poucher WA. Perfumes Cosmetics and Soaps, Chapman and Hall, London 1993: 130.
[8] Yadav SK, Gupta SK, Prabha S. Hair growth activity of Nardostachys jatamansi and Cyperus rotundus rhizomes extract on chemotherapy induced alopecia.Int J Drug Dis Herbal Res 2011; 1:52-4.
[9] Perez-Ornelas V, Cabeza M, Bratoeff E, et al. New 5alpha-reductase inhibitors: in vitro and in vivo effects. Seroids 2005; 70: 217-24.
[10] Patna P, Varghese D, Balekar N, et al. Formulation and evaluation of herbal hair oil for alopecia management. Planta indica 2006; 2:27-30.
[11] Roy RK, Thakur M, Dixit VK. Development and evaluation of Polyherbal formulation for hair growth promoting activity. J Cosm DermatoL 2007; 6:108-12.
[12] Libecco JF, Bergfeld WF. Finasteride in the treatment of alopecia.Exp Opin Pharmacother 2004; 5 993-40.
[13] Price VH, Menefee E, Strauss PC. Changes in hair weight and hair count in men with androgenetic alopecia, after application of 5% and 2% topical minoxidil, placebo or no treatment. J Amer Acad Dermatol 1999; 41:717-21.
[14] Dhanukar SA, Thahe UM.Therapeutic Approaches, Ayurveda revisited, Popular Prakashan 1989: 74-130.
[15] Gupta A. “Astangahrdayam” Chukamba Publications, Varanasi 2003: 534-35.
[16] Sastri S. “Madhavanidanam” Chukamba Publications, Varanasi 2003: 202-5.
[17] Sharmarna PS, Charak samhita, Part 2 1995:1584- 1587.
[18] Shandrdhar Samhita Granthasay, 488-490.
[19] Luanpitpong S, Nimmannit U, Pongrakhananon V, et al. Emblica (Phyllanthus emblica Linn.) fruit extract promotes proliferation in dermal papilla cell of human hair follicle. Res J Med Plant 2011; 5:95-100.
[20] Ishida H, Inaoka Y, Okada M, et al. Studies of the active substances in herbs used for hair treatment III Isolation of hair-regrowth substances from Polygara senega var. latifolia TORR et GRAY. Biol Pharma Bull 1999; 22:1249-50.
[21] Banerjee PS, Sharma M, Nema RK. Preparation, evaluation and hair growth stimulating activity of herbal hair oil. J Chem Pharma Res 2009; 1:261-67.
[22] Sabarwal N, Varghese D, Barik R,Khandelwal A, Jain A. Jain S. Development and evaluation of polyherbal formulations for hair growth activity. PharmacogNet 2009; 1:165-70.
[23] Shah CS. Qudry JS. A Text book of Pharmacognosy. 11th Ed, B.S. Shah Prakashan, Ahmadabad 1996: 119.
[24] Prajapati, Purohit and Sharma, “A Handbook of Medicinal Plants- A Complete Source Book”, Published by Agrobios (India) 2003: 52.
[25] Semalty M, Semalty A, Joshi GP, Rawat MSM. In vivo Hair Growth Activity of Herbal Formulations. Int J Pharmacol 2010; 6:53-7.
[26] Adhirajan N, Kumar TR, Shanmugasundaram N, Mary B. In vivo and in vitro evaluation of hair growth potential of Hibiscus rosa-sinensis Linn. J Ethnopharmacol 2003; 88:235-9.
[27] Thorat RM, Jadhav VM, Kadam VJ. Development and evaluation of polyherbalformulations for hair growth-promoting activity. Int J Pharma Tech Res 2009; 1:1251-54.
[28] Inaoka Y, Shakuya A, Fukazawa H, et al. Effects of herb extract on hair growth and isolation of an active substance from Polyporus umbellatus F. Chem Pharma Bull (Tokyo) 1994; 42:530-33.
[29] Ishida H, Inaoka Y, Shibatani J, et al. Studies of the active substances in herbs used for hair treatment. II. Isolation of hair regrowth substances, acetosyringone and polyporusterone A and B, from Polyporus umbellatus Fries. Biol Pharma Bull 1999; 22:1189-92.
[30] Sun A, Chia JS, Chiang CP, et al. The Chinese herbal medicine Tien-Hsien liquid inhibits cell growth and induces apoptosis in a wide variety of human cancer cells. J Alt CompMed 2005; 11:245-56.
[31] Hay IC, Jamieson M, Ormerod AD. Randomized trial of aromatherapy. Successful treatment for alopecia areata. Arch Dermatol 1998; 134:1349-52.
[32] Hashimoto K, Katsuhara T, Itoh H, et al. Monoterpenes from Asiasari Radix from Asiasarum sp. Phytochem 1990; 29:3571-74.
[33] Rho SR, Park JS, Hwang SL, et al. The hair growth promoting effect of Asiasari radix extract and it’s molecular regulation. J Dermatol Sci 2005; 38:89-97.
[34] Shimizu K, Kondo R, Sakai K, et al. Steroid 5
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Bharti M, Shrivastav A, Abid M, Khan NA. A Review on Hair Growth Regulator. JDDT [Internet]. 15Sep.2020 [cited 25Sep.2020];10(5):368-75. Available from: http://jddtonline.info/index.php/jddt/article/view/4406