A Study to Evaluate Pharmacoeconomics of Antihypertensive Drugs in a Tertiary Care Teaching Hospital

  • Nimmy N John Department of Pharmacy Practice, Net Pharmacy College, Raichur-584103 Karnataka, India
  • Athira Krishnan Department of Pharmacy Practice, Net Pharmacy College, Raichur-584103 Karnataka, India
  • JV Midhun Department of Pharmacy Practice, Net Pharmacy College, Raichur-584103 Karnataka, India
  • Riya Juan Department of Pharmacy Practice, Net Pharmacy College, Raichur-584103 Karnataka, India

Abstract

Background: Hypertension is a major public health problem associated with large health burden as well as high economic burden at individual and population levels. A prospective observational study carried out in in-patients admitted to general medicine department of tertiary care hospital to evaluate the most cost effective therapy among the monotherapy of Amlodipine and combination therapy of telmisartan + hydrochlorthiazide.


Methods: A total of 120 Hypertensive patients case records prescribed with monotherapy of Amlodipine and combination therapy of Telma H were reviewed and evaluated using descriptive statistics and ā€˜pā€™ value and assessed for their financial burden based on the cost per tablet for an year, Cost effectiveness ratio for the patients with controlled Blood Pressure by using a particular drug.


Results: Out of 120 patients females were more (59.2%) and most of them were under the age group of 41-60 years. Majority of the patients had a known history of hypertension (65%). Most of the patients were prescribed with Telma H 40/12.5mg (40%) followed with Amlong 5mg (35.8%). There was a significant positive correlation (i.e., p value= 0.05) between persistence patterns of patients with drug therapy. Probability of patients with controlled Blood Pressure taking Amlong 10 mg were 82.35% followed by patients with Amlong 5mg.


Conclusion: This study clearly showed that monotherapy of amlodipine is the most cost effective therapy than combination therapy of Telma H in order to reduce financial burden to the patient as well as to decrease the complications.


Keywords: Hypertension, Pharmacoeconomics, Cost effectiveness, Blood Pressure.

Keywords: Hypertension, Pharmacoeconomics, Cost effectiveness, Blood Pressure

Downloads

Download data is not yet available.

Author Biographies

Nimmy N John, Department of Pharmacy Practice, Net Pharmacy College, Raichur-584103 Karnataka, India

Department of Pharmacy Practice, Net Pharmacy College, Raichur-584103 Karnataka, India

Athira Krishnan, Department of Pharmacy Practice, Net Pharmacy College, Raichur-584103 Karnataka, India

Department of Pharmacy Practice, Net Pharmacy College, Raichur-584103 Karnataka, India

JV Midhun, Department of Pharmacy Practice, Net Pharmacy College, Raichur-584103 Karnataka, India

Department of Pharmacy Practice, Net Pharmacy College, Raichur-584103 Karnataka, India

Riya Juan, Department of Pharmacy Practice, Net Pharmacy College, Raichur-584103 Karnataka, India

Department of Pharmacy Practice, Net Pharmacy College, Raichur-584103 Karnataka, India

References

1. Mekonnen HS, Gebrie MH, Eyasu KH, Gelagay AA. Drug adherence for antihypertensive medications and its determinants among adult antihypertensive patients in chronic clinics of referral hospitals in Northwest Ethiopia. Mekonnen et al. BMC Pharmacol and toxicol, 2017; 18(27):1-10.
2. Bhusal A, Jadhav PR, Deshmukh YA. Assessment of medication adherence among hypertensive patients: a cross-sectional study. Int J basics Clin Pharmacol, 2016; 5(4):1606-1612.
3. Bolivar JJ. Essential Hypertension an approach to its etiology and neurogenic pathophysiology. Int J Hypertens, 2013; 2013:1-11.
4. Alefan Q, Tariq AR, Ibrahim MI, Ayub A. Cost effectiveness of antihypertensive treatments in Malaysia. Malaysian J pharm sci, 2009; 7(2):137-152.
5. Ilesanmi OS, Kehinde Ige O, Adebiyi AO. The managed hypertensive: the costs of blood pressure control in Nigeria town. Pan Afr Med J. 2012; 12(96):1-9.
6. Dhivya PS, Swathy G, Siddhartha P. Pharmacoeconomics of antihypertensive drugs prescribed in a multispeciality hospital in South India. Asian j pharm, 2014; 8:178-182.
7. Esposti LD, Martino MD, Saragoni S, Sgreccia A, Capone A, Buda S, Esposti ED. Pharmacoeconomics of antihypertensive drug treatment: An analysis of how long patients remain on various antihypertensive therapies. The J Clin Hypertens, 2004; 6(2):76-83.
Statistics
198 Views | 150 Downloads
How to Cite
1.
John NN, Krishnan A, Midhun J, Juan R. A Study to Evaluate Pharmacoeconomics of Antihypertensive Drugs in a Tertiary Care Teaching Hospital. JDDT [Internet]. 14Aug.2020 [cited 23Apr.2021];10(4-s):176-80. Available from: http://jddtonline.info/index.php/jddt/article/view/4227