EVALUATION OF ANTI-ULCER ACTIVITY OF METHANOLIC EXTRACT OF JASMINUM TRICHOTOMUM LEAVES IN ALBINO RATS

  • K Sumathi
  • Reena SR Babu JKKMMRF college of pharmacy, B.Komarapalayam. Namakkal dist, Tamil nadu
  • A Suresh Department of Pharmaceutical Chemistry, J K K Munirajah Medical Research Foundation College of Pharmacy , Komarapalayam,Namakkal (dt),Tamilnadu,India.
  • N Senthilkumar Department of Pharmaceutical Chemistry, J K K Munirajah Medical Research Foundation College of Pharmacy , Komarapalayam,Namakkal (dt),Tamilnadu,India.

Abstract

Jasminum trichotomum Leaves (oleaceae) has been reported various medicinal uses including analgesic, antipyretic and anti-inflammatory activities. We studied the anti-ulcer potential of the methanolic extract in order to validate ethanobotanical claim regarding the plant use in the above mentioned disorders. Gastro protective potential of the methanolic extract of Jasminum trichotomum (200 and 400 mg/kg/body weight) was studied on ethanol induced ulcers. The results of the present study shows that the methanol extracts of Jasminum trichotomum exert gastro-protective action against ethanol induced ulcer model. The parameters studied were ulcer index, total acidity and free acidity. These findings could justify, at least partially, the inclusion of this plant in the management of gastric disorders in traditional medicine.

KEYWORDS: Analgesic, Antipyretic, Anti-inflammatory, Anti-ulcer, Jasminum trichotomum

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Author Biography

Reena SR Babu, JKKMMRF college of pharmacy, B.Komarapalayam. Namakkal dist, Tamil nadu
Pharmaceutical chemistry
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How to Cite
Sumathi, K., Babu, R., Suresh, A., & Senthilkumar, N. (2013). EVALUATION OF ANTI-ULCER ACTIVITY OF METHANOLIC EXTRACT OF JASMINUM TRICHOTOMUM LEAVES IN ALBINO RATS. Journal of Drug Delivery and Therapeutics, 3(2). https://doi.org/10.22270/jddt.v3i2.418