Morphology, Phytochemistry and Pharmacological Activity of Vitex negundo: An Overview

  • Yogendra Singh Department of Pharmacology, BIU College of Pharmacy, Bareilly International University, Bareilly-243006, U.P., India
  • Pankaj Mishra Department of Pharmaceutical Chemistry, Keshlata College of Pharmacy, Bareilly International University, Bareilly-243006, U.P., India
  • Pushpendra Kannojia Department of Pharmacology, BIU College of Pharmacy, Bareilly International University, Bareilly-243006, U.P., India

Abstract

Now days a herbal and traditional medicines mostly used in all over the world according to WHO, about 60 to 65% world population practicing herbal and traditional medicines. Vitex negundo Linn. is an aromatic herb belong to family Verbenaceae. It is also known as Nirgundi, Five leaved chaste tree. Plants have many chemical constituents as flavonoids, volatile oil, triterpenes, diterpenes, sesquiterpenes, lignan, flavones, glycosides, iridoid glycosides and stilbene derivative. These chemical constituents are present in each part of the plant. Vitex negundo extract have various pharmacological activities such as anti-inflammatory, antipyretic, anti-arthritic, antioxidant, analgesic activity, antibacterial activity, antitumor activity, anti-amnesic activity, anxiolytic activity, Nephroprotective activity, anti-HIV activity, Antitubercular activity, antieosinophilic activity, anti-snake venom activity. This review article provides depth information related to plant morphology, cultivation, chemical constitutes, pharmacological activities and their medicinal uses.


Keywords: Vitex negundo, Nirgundi, Casticin, Anti-Gout Activity

Keywords: Vitex negundo, Nirgundi, Casticin, Anti-Gout Activity

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Author Biographies

Yogendra Singh, Department of Pharmacology, BIU College of Pharmacy, Bareilly International University, Bareilly-243006, U.P., India

Department of Pharmacology, BIU College of Pharmacy, Bareilly International University, Bareilly-243006, U.P., India

Pankaj Mishra, Department of Pharmaceutical Chemistry, Keshlata College of Pharmacy, Bareilly International University, Bareilly-243006, U.P., India

Department of Pharmaceutical Chemistry, Keshlata College of Pharmacy, Bareilly International University, Bareilly-243006, U.P., India

Pushpendra Kannojia, Department of Pharmacology, BIU College of Pharmacy, Bareilly International University, Bareilly-243006, U.P., India

Department of Pharmacology, BIU College of Pharmacy, Bareilly International University, Bareilly-243006, U.P., India

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Singh Y, Mishra P, Kannojia P. Morphology, Phytochemistry and Pharmacological Activity of Vitex negundo: An Overview. JDDT [Internet]. 15Jun.2020 [cited 2Jul.2020];10(3-s):280-5. Available from: http://jddtonline.info/index.php/jddt/article/view/4173