Studies on Antioxidant and Anti-obesity Activity of Salvia hispanica (Chia) Seeds Extracts

  • Subbaiyan Rubavathi Department of Biotechnology, K .S. Rangasamy college of Technology, Tiruchengode – 637 215, Namakkal, Tamil Nadu, India
  • Ganesan Ayyappadasan Department of Biotechnology, K .S. Rangasamy college of Technology, Tiruchengode – 637 215, Namakkal, Tamil Nadu, India
  • Nagarajan Sangeetha Department of Biotechnology, K .S. Rangasamy college of Technology, Tiruchengode – 637 215, Namakkal, Tamil Nadu, India
  • Thangavel Harini Department of Biotechnology, K .S. Rangasamy college of Technology, Tiruchengode – 637 215, Namakkal, Tamil Nadu, India
  • Dhanuskodi Saranya Department of Biotechnology, K .S. Rangasamy college of Technology, Tiruchengode – 637 215, Namakkal, Tamil Nadu, India
  • Prakash Harshapradha Department of Biotechnology, K .S. Rangasamy college of Technology, Tiruchengode – 637 215, Namakkal, Tamil Nadu, India

Abstract

Obesity is a condition in which large amount of fat is stored in adipose tissue. Obesity is the greatest risk for many diseases like coronary heart disease, type 2 diabetes millions associated with insulin resistance, arthritis disorder, hypertension and cancers. Currently, the available drugs for obesity have been associated with number of side effects when compared with allopathic drugs. Salvia hispanica was one of the member of Lamiaceae family, collected to study the antiobesity activity. Extraction of Salvia hispanica using different solvents was done and tested for the presence of phytochemical constituents and the antimicrobial activity was monitored to evaluate the zone of inhibition. Further, antioxidant potential activity such as DPPH, FRAP and H2O2 assay was studied. Percentage of inhibition of Salvia hispanica was calculated and was observed as in capturing the free radicals present in the body. The surface and cross-sectional morphology Salvia hispanica extract nanoparticles was examined by using SEM. High ALA content make chia a perfect as it is associated with lower incidence of Cardiovascular diseases. This metabolic syndrome is mediated by inflammatory pathways. Hence, the in vitro activity of anti-inflammatory assay was performed by inhibition of albumin denaturation and anti-obesity activity was performed by lipase inhibition assay. Thus the result indicates that the seed extracts of Salvia hispanica possess antiobesity activity.


Keywords: Salvia hispanica, anti-obesity, cholesterol, Antioxidant, lipase inhibition

Keywords: Salvia hispanica, anti-obesity, cholesterol, Antioxidant, lipase inhibition

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Author Biographies

Subbaiyan Rubavathi, Department of Biotechnology, K .S. Rangasamy college of Technology, Tiruchengode – 637 215, Namakkal, Tamil Nadu, India

Department of Biotechnology, K .S. Rangasamy college of Technology, Tiruchengode – 637 215, Namakkal, Tamil Nadu, India

Ganesan Ayyappadasan, Department of Biotechnology, K .S. Rangasamy college of Technology, Tiruchengode – 637 215, Namakkal, Tamil Nadu, India

Department of Biotechnology, K .S. Rangasamy college of Technology, Tiruchengode – 637 215, Namakkal, Tamil Nadu, India

Nagarajan Sangeetha, Department of Biotechnology, K .S. Rangasamy college of Technology, Tiruchengode – 637 215, Namakkal, Tamil Nadu, India

Department of Biotechnology, K .S. Rangasamy college of Technology, Tiruchengode – 637 215, Namakkal, Tamil Nadu, India

Thangavel Harini, Department of Biotechnology, K .S. Rangasamy college of Technology, Tiruchengode – 637 215, Namakkal, Tamil Nadu, India

Department of Biotechnology, K .S. Rangasamy college of Technology, Tiruchengode – 637 215, Namakkal, Tamil Nadu, India

Dhanuskodi Saranya, Department of Biotechnology, K .S. Rangasamy college of Technology, Tiruchengode – 637 215, Namakkal, Tamil Nadu, India

Department of Biotechnology, K .S. Rangasamy college of Technology, Tiruchengode – 637 215, Namakkal, Tamil Nadu, India

Prakash Harshapradha, Department of Biotechnology, K .S. Rangasamy college of Technology, Tiruchengode – 637 215, Namakkal, Tamil Nadu, India

Department of Biotechnology, K .S. Rangasamy college of Technology, Tiruchengode – 637 215, Namakkal, Tamil Nadu, India

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Rubavathi S, Ayyappadasan G, Sangeetha N, Harini T, Saranya D, Harshapradha P. Studies on Antioxidant and Anti-obesity Activity of Salvia hispanica (Chia) Seeds Extracts. JDDT [Internet]. 15Jun.2020 [cited 2Jul.2020];10(3-s):98-06. Available from: http://jddtonline.info/index.php/jddt/article/view/4169