The Influence of Green Tea Infusion (Camellia sinensis) on Renal Histopathological Overview of Male White Rats (Rattus Norvegicus) Sprague Dawley Strain Induced by Ethanol

  • Muhartono Muhartono Department of Pathology, Medical Faculty of Lampung University, Lampung, Indonesia
  • Katya Rizqita Fitriana Department of Pathology, Medical Faculty of Lampung University, Lampung, Indonesia

Abstract

Aims: This sudy aims to determine the effect infusion  of green tea (Camellia sinensis) to the renal histopathology picture of male white rats (Rattus norvegicus) Sprague dawley strain ethanol-induced.


Methods: This study used 30 rats divided into 5 groups. The negative control (K-) was given distilled water 2 mL/day, the positive control (K +) was given ethanol 2 mL/day, the treatment group (P1, P2, P3) was given ethanol 2 mL and green tea infusion with respective doses of 0.375, 0.75 and 1.5 grams orally for 14 days. Then the renal retrieval is done to be examined microscopically.


Results: The mean kidney damage score obtained was K- = 0.36; K + = 3.24; P1 = 2.52; P2 = 2,4; and P3 = 2.2. Data analysis with One Way Anova Test and continued with Pos Hoc and found significant differences in K- to K+, P1, P2, P3; K+ is significant to K-, P1, P2, P3; and P1, P2, P3 are significant to K- & K+.


Conclusion: There is an effect of infusion of green tea (Camellia sinensis) on the renal histopathological picture of male white rats (Rattus norvegicus) ethanol-induced Sprague dawley strain.


Keywords: alcohol, antioxidant, ethanol, green tea, renal histopathology

Keywords: alcohol, antioxidant, ethanol, green tea, renal histopathology

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Author Biographies

Muhartono Muhartono, Department of Pathology, Medical Faculty of Lampung University, Lampung, Indonesia

Department of Pathology, Medical Faculty of Lampung University, Lampung, Indonesia

Katya Rizqita Fitriana, Department of Pathology, Medical Faculty of Lampung University, Lampung, Indonesia

Department of Pathology, Medical Faculty of Lampung University, Lampung, Indonesia

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Muhartono M, Fitriana K. The Influence of Green Tea Infusion (Camellia sinensis) on Renal Histopathological Overview of Male White Rats (Rattus Norvegicus) Sprague Dawley Strain Induced by Ethanol. JDDT [Internet]. 15Jun.2020 [cited 2Jul.2020];10(3-s):111-5. Available from: http://jddtonline.info/index.php/jddt/article/view/4101