A Review on Epilepsy and its Management

  • V.V. Potnis Department of Pharmaceutics, JSPM’S JSCOPR, Hadapsar, Pune, INDIA, 411028
  • Ketan G. Albhar Department of Pharmaceutics, JSPM’S JSCOPR, Hadapsar, Pune, INDIA, 411028
  • Pritamsinh Arjun Nanaware Department of Pharmaceutics, JSPM’S JSCOPR, Hadapsar, Pune, INDIA, 411028
  • Vishal S. Pote Department of Pharmaceutics, JSPM’S JSCOPR, Hadapsar, Pune, INDIA, 411028

Abstract

Today, people face various types of stress in everyday fast life and most people in the world suffer from various neurological disorder. Epilepsy is one of the most common neurological disorders of the brain, affecting about 50 million people around the world, and 90% of them are coming from developing countries. Genetic factors and brain infection, stroke, tumors and epilepsy cause high fever. It imposes a great economic burden on the health systems of countries associated with stigma and discrimination against the patient and also his family in the community, in the workplace, school and home. Many patients with epilepsy suffer from severe emotional stress, behavioral disorders and extreme social isolation. There are many different types of seizure and mechanisms by which the brain generates seizures. The two features of generating seizures are hyperexcitability of neurons and a hyper synchronousneural circuits. A variety of mechanisms alters the balance between excitation and inhibition in predisposing brain local or generalized hyperexcitability region and a hypersynchronia. Purpose of the review is to discuss the history, epidemiology, etiology, pathophysiology, classification of epilepsy, symtomps, diagnosis, management of epilepsy and future trends.


Keywords: Anti-epileptic drugs, pathophysiology, seizures, epidemiology, hypersynchrony

Keywords: Anti-epileptic drugs, pathophysiology, seizures, epidemiology, hypersynchrony

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Author Biographies

V.V. Potnis, Department of Pharmaceutics, JSPM’S JSCOPR, Hadapsar, Pune, INDIA, 411028

Department of Pharmaceutics, JSPM’S JSCOPR, Hadapsar, Pune, INDIA, 411028

Ketan G. Albhar, Department of Pharmaceutics, JSPM’S JSCOPR, Hadapsar, Pune, INDIA, 411028

Department of Pharmaceutics, JSPM’S JSCOPR, Hadapsar, Pune, INDIA, 411028

Pritamsinh Arjun Nanaware, Department of Pharmaceutics, JSPM’S JSCOPR, Hadapsar, Pune, INDIA, 411028

Department of Pharmaceutics, JSPM’S JSCOPR, Hadapsar, Pune, INDIA, 411028

Vishal S. Pote, Department of Pharmaceutics, JSPM’S JSCOPR, Hadapsar, Pune, INDIA, 411028

Department of Pharmaceutics, JSPM’S JSCOPR, Hadapsar, Pune, INDIA, 411028

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Potnis V, Albhar KG, Nanaware P, Pote VS. A Review on Epilepsy and its Management. JDDT [Internet]. 15May2020 [cited 1Jun.2020];10(3):273-9. Available from: http://jddtonline.info/index.php/jddt/article/view/4090