Nanoparticles: An Overview
Nanoparticles are the preparations having size in nanometers. Particulate systems like nanoparticles have been used asÂ a physical approach to alter and improve the pharmacokinetic and pharmacodymanic properties of various types of drug molecules.They have been used in vivo to protect the drug entity in the systemic circulation, restrict access of the drug to the choosen sites and to deliver the drug at a controlled and sustained rate to the site of action. Various polymers have been used in the formulation of nanoparticles for the drug delivery researchÂ to increase therapeutic benefit, while minimizing side effects.Here we review various aspectsÂ of nanoparticleÂ formulation, characterization, effect of their characteristics and their applications in delivery of drug molecules and therapeutic genes.
Keywords : Nanoparticles, controlled and sustained rate, polymers, characterization, evaluation
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).