The Flavonoid Compounds from Zanthoxylum leprieurii Guill. et Perr (Rutaceae) Extracts and their Antioxidant Activity against ABTS•+

  • Yoro TINE Laboratoire de Chimie Organique et Thérapeutique, Faculté de Médecine, Pharmacie et Odontologie, Université Cheikh Anta Diop, BP : 5005 Dakar-Fann, Sénégal
  • Alioune DIALLO Laboratoire de Chimie Organique et Thérapeutique, Faculté de Médecine, Pharmacie et Odontologie, Université Cheikh Anta Diop, BP : 5005 Dakar-Fann, Sénégal
  • Idrissa NDOYE Laboratoire de Chimie Organique et Thérapeutique, Faculté de Médecine, Pharmacie et Odontologie, Université Cheikh Anta Diop, BP : 5005 Dakar-Fann, Sénégal
  • Yin YANG Université de Corse, UMR CNRS 6134 SPE, Laboratoire de Chimie des Produits Naturels, Campus Grimaldi, BP 52, F-20250 Corte, France
  • Franck RENUCCI Université de Corse, UMR CNRS 6134 SPE, Laboratoire de Chimie des Produits Naturels, Campus Grimaldi, BP 52, F-20250 Corte, France
  • Rokhya Sylla Guèye Laboratoire de Chimie Organique et Thérapeutique, Faculté de Médecine, Pharmacie et Odontologie, Université Cheikh Anta Diop, BP : 5005 Dakar-Fann, Sénégal
  • Mamadou Baldé Laboratoire de Chimie Organique et Thérapeutique, Faculté de Médecine, Pharmacie et Odontologie, Université Cheikh Anta Diop, BP : 5005 Dakar-Fann, Sénégal
  • Adama Diédhiou Laboratoire de Chimie Organique et Thérapeutique, Faculté de Médecine, Pharmacie et Odontologie, Université Cheikh Anta Diop, BP : 5005 Dakar-Fann, Sénégal
  • Djibril Fall Laboratoire de Chimie Organique et Thérapeutique, Faculté de Médecine, Pharmacie et Odontologie, Université Cheikh Anta Diop, BP : 5005 Dakar-Fann, Sénégal
  • Matar Seck Laboratoire de Chimie Organique et Thérapeutique, Faculté de Médecine, Pharmacie et Odontologie, Université Cheikh Anta Diop, BP : 5005 Dakar-Fann, Sénégal
  • Jean-Marie Desjobert Université de Corse, UMR CNRS 6134 SPE, Laboratoire de Chimie des Produits Naturels, Campus Grimaldi, BP 52, F-20250 Corte, France
  • Jean COSTA Université de Corse, UMR CNRS 6134 SPE, Laboratoire de Chimie des Produits Naturels, Campus Grimaldi, BP 52, F-20250 Corte, France
  • Alassane WELE Laboratoire de Chimie Organique et Thérapeutique, Faculté de Médecine, Pharmacie et Odontologie, Université Cheikh Anta Diop, BP : 5005 Dakar-Fann, Sénégal
  • Julien PAOLINI Université de Corse, UMR CNRS 6134 SPE, Laboratoire de Chimie des Produits Naturels, Campus Grimaldi, BP 52, F-20250 Corte, France

Abstract

Screening of flavonoid compounds in fruit, leaf, stem and root bark extracts of Z. leprieurii was achieved by liquid chromatography (LC) coupled with tandem mass spectrometry (MS2). Among the 186 reference compounds tested, four flavonoids were identified in one or other of the organ extracts from each plant (fruit, leaf, root barks and stem): neodiosmin and hesperidin were identified in all extracts. The presence of datiscin was reported only in leaves while that of rutin was identified in fruits and leaves. Of these four flavonoids, three (neodiosmin, datiscin and rutin) are detected for the first time in Z. leprieurii. The antioxidant properties of different extracts were tested regarding their scavenging activities on ABTS•+ radical. Fruit, leaf and stem extracts had low antioxidant potential and root bark extracts exhibited very low antioxidant activity.


Keywords: Zanthoxylum leprieurii, flavonoids, LC-MS/MS and antioxidant activity.

Keywords: Zanthoxylum leprieurii, flavonoids, LC-MS/MS, antioxidant activity

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TINE Y, DIALLO A, NDOYE I, YANG Y, RENUCCI F, Guèye RS, Baldé M, Diédhiou A, Fall D, Seck M, Desjobert J-M, COSTA J, WELE A, PAOLINI J. The Flavonoid Compounds from Zanthoxylum leprieurii Guill. et Perr (Rutaceae) Extracts and their Antioxidant Activity against ABTS•+. JDDT [Internet]. 15Apr.2020 [cited 22Sep.2021];10(2-s):120-4. Available from: http://jddtonline.info/index.php/jddt/article/view/4010