TO INVESTIGATE AND ASSES WHY SOME FOOD/ DIETARY SUPPLEMENTS ARE HEALTH HAZARDOUS

  • Neha Rani Department of Pharmacy, IEC Group of Institutions, Greater Noida, India
  • Bhanu PS Sagar Department of Pharmacy, IEC Group of Institutions, Greater Noida, India
  • Sandeep Kumar Shukla Professor and director, Department of Pharmacy, IEC Group of Institutions, Greater Noida, India

Abstract

Toxic ingredients of Pharmaceutical as well as Food grade food supplements / Dietary Supplement are Pygeum, Caffeine / Caffeine extract, Omega 3 fatty acid (source fish oil, flaxseed oil, or cod liver oil), Ephedrine (Ephedra sinica) , Usnic acid, Kava-Kava (Piper methysticum), Gugulipid (Comiphora mukul), Liquorice (Glycyrrhiza glabra),  Ginseng  (Panax ginseng, Panax japonicus, Panax trifolius, Panax zingiberensis, Panax bipinnatifidus), St. John's wort (Hypericum perforatum) etc. Caffeine (1,3,7-trimethylxanthine) is an alkaloid of the methylxanthine family known as a central nervous system stimulant through its adenosine antagonist action. Caffeine is a naturally found in the leaves, seeds and/or fruits of at least 63 plant species worldwide. Caffeine produces psychoactive responses (alertness, mood change), neurological condition (infant hyperactivity, Parkinson’s disease), metabolic disorders (diabetes, gallstones), and gonad and liver function. However, high doses may produce negative effects in some sensitive individuals, including anxiety, tachycardia and insomnia recommended upper limits of caffeine for healthy adults below 300-500 mg daily, pregnant women must stay below 150-200 mg daily and children should stay below 50 mg daily. Amounts exceeding 700 milligrams of caffeine can be dangerous.


Key words: Caffeine, CNS stimulant

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How to Cite
Rani, N., Sagar, B., & Shukla, S. (2013). TO INVESTIGATE AND ASSES WHY SOME FOOD/ DIETARY SUPPLEMENTS ARE HEALTH HAZARDOUS. Journal of Drug Delivery and Therapeutics, 3(1). https://doi.org/10.22270/jddt.v3i1.392