The Essential oil of Eucalyptus alba L. Growing on the Salt Zone of Fatick (Senegal) as a Source of 1,8Cineole and Their Antibacterial Activity

  • Yoro Tine Laboratoire de Chimie Organique et Thérapeutique, Faculté de Médecine, Pharmacie et Odontologie, Université Cheikh Anta Diop, BP: 5005 Dakar-Fann, Sénégal
  • Alioune Diallo
  • Abdoulaye Diop
  • Jean Costa
  • Cheikh Saad Bouh Boye
  • Alassane Wélé
  • Julien Paolini


Members of the genus Eucalyptus are potential sources of number of commercial essential oils and aromachemicals. In present study, the essential oils isolated by hydrodistillation from the leaves of Eucalyptus alba were analyzed by GC-FID and GC-MS. Essential oil yields ranged from 2.41 to 4.35%. In total 18 constituents were identified, accounting for 99.0 to 99.7% of the total compositions. 1,8-cineole was present in all samples as the major component (76.5-88.1%). In addition to this compound, others that were found including limonene (3.8–8.6%), α-terpineol (1.4–2.8%), globulol (1.3–6.3%) and α-pinene (1.5–1.8%). The essential oil showed a strong antibacterial activity against S. aureus ATCC 29213 which is translated by an MIC of 1.25 mg/mL and good activity against E. coli ATCC 25922 (6.25 mg/mL) and E. faecalis ATCC 29212 (6.25 mg/mL). To our knowledge, our study is the first report of E. alba essential oils characterized by a high 1,8-cineole content (>76.5%). They may have potential applications in food and pharmaceutical products.

Keywords: Eucalyptus alba, essential oils, antibacterial activity, 1,8-cineole and GC-SM

Keywords: Eucalyptus alba, essential oils, antibacterial activity, 1,8-cineole and GC-SM


Download data is not yet available.


[1] Edris AE, Pharmaceutical and therapeutic Potentials of essential oils and their individual volatile constituents: a review. Phytotherapy Research. 2007; 21(4):308–323.
[2] Bakkali F., Averbeck S., Averbeck D., and Idaomar M. Biological effects of essential oils--a review. Food and Chemical Toxicology: An International Journal Published for the British Industrial Biological Research Association. 2008; 46(2):446–475.
[3] Bruneton J. Pharmacognosie : Phytochimie, Plantes médicinales. 4e édition Tec & Doc Lavoisier, Paris; Cachan. 2009.
[4] Vigan M. and Besançon C.H.U. Les huiles essentielles: leur retour et leur toxicité. Progrès En Dermato-Allergologie: Bordeaux 2009; 15:123.
[5] Preedy V.R. Essential Oils in Food Preservation, Flavor and Safety. Academic Press. 2015.
[6] Folliard, T. La bible Larousse des huiles essentielles. Larousse. 2016.
[7] Pavia D.L., Kriz G.S., Lampman G.M., and Engel R.G. A Microscale Approach to Organic Laboratory Techniques. Cengage Learning. 2016.
[8] Vecchio, M.G., Loganes, C., and Minto, C. Beneficial and Healthy Properties of Eucalyptus Plants: A Great Potential Use. The Open Agriculture Journal. 2016; 10(1):5257.
[9] Bhowal M. and Gopal M. Eucalyptol: Safety and Pharmacological Profile. RGUHS J Pharm Sci. 2016; 5:125–131.
[10] Jalilzadeh-Amin G. and Maham, M. The application of 1,8-cineole, a terpenoid oxide present in medicinal plants, inhibits castor oil-induced diarrhea in rats. Pharmaceutical Biology. 2015; 53(4):594–599.
[11] Ghaffar A., Yameen M., Kiran S., Kamal S., Jalal F., Munir B., et al. Chemical Composition and in-Vitro Evaluation of the Antimicrobial and Antioxidant Activities of Essential Oils Extracted from Seven Eucalyptus Species. Molecules. 2015; 20(11):20487–20498.
[12] De Brink M. and Achigan-Dako, E.G. Fibres. PROTA. 2012.
[13] Giffard P.-L. (1972) Les essais d’introduction d’Eucalyptus menés au CRA de Bambey. Accessed March 2, 2019.
[14] Barka Ndiaye E.H., Talla Gueye M., Ndiaye I., Diop S.M., Diop M.B., Fauconnier M.-L., et al. Chemical composition of essential oils and hydrosols of three Eucalyptus species from Senegal: Eucalyptus alba Renv, Eucalyptus camaldulensis Dehnh and Eucalyptus tereticornis Hook. American Journal of Essential Oils and Natural Products. 2017; 5(1):1–7.
[15] O. Oyedeji A., Ekundayo O., Olawore O.N., Adeniyi B.A., and Koenig W.A. Antimicrobial activity of the essential oils of five Eucalyptus species growing in Nigeria. Fitoterapia. 1999; 70(5):526–528.
[16] Cimanga K., Kambu K., Tona L., Apers S., De Bruyne T., Hermans N., et al. Correlation between chemical composition and antibacterial activity of essential oils of some aromatic medicinal plants growing in the Democratic Republic of Congo. Journal of Ethnopharmacology. 2002; 79(2):213–220.
[17] Mondello L., Verzera A., Bonaccorsi I., Chowdhury J.U., Yusef M., and Begum J. Studies in the Essential Oil Bearing Plants of Bangladesh. Part V. Composition of the Leaf Oils of Eucalyptus citriodora Hook and E. alba Reinw. ex Blume. Journal of Essential Oil Research. 1998; 10(2):185–188.
[18] Samaté A.D., Nacro M., Menut C., Lamaty G., and Bessière J.M. Aromatic Plants of Tropical West Africa. VII. Chemical Composition of the Essential Oils of two Eucalyptus Species (Myrtaceae) from Burkina Faso: Eucalyptus alba Muell. and Eucalyptus camaldulensis Dehnardt. Journal of Essential Oil Research. 1998; 10(3):321–324.
[19] Council of Europe. European pharmacopoeia. 3rd ed. Council of Europe, Strasbourg. 1997.
[20] Adams R.P. and others, Identification of essential oil components by gas chromatography/mass spectrometry. Allured publishing corporation. 2007.
[21] Joulain D. and König W.A. The atlas of spectral data of sesquiterpene hydrocarbons. EB-Verlag. 1998.
[22] NIST (National Institute of Standards and Technology), N. PC Version of the NIST/EPA/NIH Mass Spectra Library. 2008.
[23] Tine, Y., Diop, A., Diatta, W., Desjobert, J.-M., Boye, C.S.B., Wélé, A., Costa, J., Paolini, J. Chemical diversity and antimicrobial activity of volatile compounds from Zanthoxylum zanthoxyloides Lam. according to compound classes, plant organs and Senegalese sample locations. Chemistry and Biodiversity. e1600125. 2016.
[24] Wikle, M.A. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically: approved standard. CLSI (NCCLS). 2006; 26:M7–A7.
[25] Oyedeji A.O., Olawore O.N., Ekundayo O., and Koenig, W.A. Volatile leaf oil constituents of three Eucalyptus species from Nigeria. Flavour and Fragrance Journal. 1999; 14(4):241–244.
[26] Cimanga K., Apers S., Bruyne T. de, Miert S.V., Hermans N., Totté J., et al. Chemical Composition and Antifungal Activity of Essential Oils of Some Aromatic Medicinal Plants Growing in the Democratic Republic of Congo. Journal of Essential Oil Research. 2002; 14(5):382–387.
2 Views | 17 Downloads
How to Cite
Tine Y, Diallo A, Diop A, Costa J, Boye CSB, Wélé A, Paolini J. The Essential oil of Eucalyptus alba L. Growing on the Salt Zone of Fatick (Senegal) as a Source of 1,8Cineole and Their Antibacterial Activity. JDDT [Internet]. 15Feb.2020 [cited 27Feb.2020];10(1-s):140-3. Available from: