GC-MS Analysis of Bioactive Compounds and Phytochemical Evaluation of the Ethanolic Extract of Gomphrena globosa L. Flowers

  • Azmat Unnisa Esmat Department of pharmaceutics, Deccan School of Pharmacy, Dar-us-salam, Aghapura, Hyderabad, telangana-500001
  • Sirisha Mittapally Department of pharmaceutics, Deccan School of Pharmacy, Dar-us-salam, Aghapura, Hyderabad, telangana-500001
  • Safiya Begum Department of pharmaceutics, Deccan School of Pharmacy, Dar-us-salam, Aghapura, Hyderabad, telangana-500001

Abstract

Gomphrena globosa (L.) has high medicinal values. All parts are been used as folk medicines. The extract of whole plant / flowers has shown different phytochemical constituents with various clinical properties. These phytochemicals recognised are responsible for various activities such as anti-inflammatory, anticancer, antibacterial, analgesic and cytotoxic. The ethanolic extract of Gomphrena globosa L. flowers of biochemical test indicates the presence of sterols, triterpenoid, tannins, phenols and flavonoids, and on GC-MS analysis it has shown 11 phytochemical compounds with different pharmacological activities. The major bioactive compounds are Docosanoic Acid, Docosyl Ester (25.404%) and Hexatriacontane (24.324%), has proven anti-inflammatory activity.


Keywords: Gomphrena globose L., phytochemical constituents, GC-MS and anti-inflammatory.

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Author Biographies

Azmat Unnisa Esmat, Department of pharmaceutics, Deccan School of Pharmacy, Dar-us-salam, Aghapura, Hyderabad, telangana-500001

Department of pharmaceutics, Deccan School of Pharmacy, Dar-us-salam, Aghapura, Hyderabad, telangana-500001

Sirisha Mittapally, Department of pharmaceutics, Deccan School of Pharmacy, Dar-us-salam, Aghapura, Hyderabad, telangana-500001

Department of pharmaceutics, Deccan School of Pharmacy, Dar-us-salam, Aghapura, Hyderabad, telangana-500001

Safiya Begum, Department of pharmaceutics, Deccan School of Pharmacy, Dar-us-salam, Aghapura, Hyderabad, telangana-500001

Department of pharmaceutics, Deccan School of Pharmacy, Dar-us-salam, Aghapura, Hyderabad, telangana-500001

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Esmat AU, Mittapally S, Begum S. GC-MS Analysis of Bioactive Compounds and Phytochemical Evaluation of the Ethanolic Extract of Gomphrena globosa L. Flowers. JDDT [Internet]. 15Mar.2020 [cited 3Jul.2020];10(2):53-8. Available from: http://jddtonline.info/index.php/jddt/article/view/3914