Formulation and Evaluation of Etoricoxib Herbal Gel for Analgesic Activity

  • Pratyush Jain Sarvepalli Radhakrishnan University, Bhopal (M.P.) India
  • Anjana Bhardwaj Sarvepalli Radhakrishnan University, Bhopal (M.P.) India
  • Alok Pal Jain Sarvepalli Radhakrishnan University, Bhopal (M.P.) India

Abstract

Medicinal plants play an imperative function in the development of potent therapeutic agents. The existing study has been undertaken with the plan to formulate and evaluate the etoricoxib herbal gel containing Buchanania lanzan extract for the management and treatment of pain. The etoricoxib herbal gel formulation was intended by using etoricoxib, menthol, linseed oil with different polymers and additives in the composition of gel. Formulated gel was evaluated in terms of various evaluation parameters as physicochemical assessment, pH, viscosity and spreadibility. Further, formulated etoricoxib herbal gel was investigated for analgesic activity by using hot-plate and acetic acid induced writhing methods. The obtained findings conclude that formulated etoricoxib herbal gel is the appropriate option for the treatment of pain and such other indications.


Keywords: Pain, Analgesic, Etoricoxib, Buchanania lanzan

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References

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Jain P, Bhardwaj A, Jain AP. Formulation and Evaluation of Etoricoxib Herbal Gel for Analgesic Activity. JDDT [Internet]. 23Dec.2019 [cited 9Aug.2022];9(2):628-31. Available from: http://jddtonline.info/index.php/jddt/article/view/3816