Polyphenol Contents and Antioxidant Activity of Ethanolic and Aqueous Algerian Propolis Extracts (Region of Serdj el ghoul)

  • El-Khamsa Soltani Laboratory of Applied Biochemistry, faculty of Nature and Life Sciences, University Ferhat Abbas Sétif 1, 19000, Algeria
  • Kamel Mokhnache Laboratory of Applied Biochemistry, faculty of Nature and Life Sciences, University Ferhat Abbas Sétif 1, 19000, Algeria
  • Noureddine Charef Laboratory of Applied Biochemistry, faculty of Nature and Life Sciences, University Ferhat Abbas Sétif 1, 19000, Algeria

Abstract

Aqueous and ethanolic extracts (EAP and EEP) of propolis sample collected from Serdj El Ghoul, region of Sétif (east of Algeria), were prepared and evaluated to identify their biological activities. Total phenolic contents were determined using Folin-Ciocalteu reagent and found to be 164,690 ± 0,044 (EAP), 155,078 ± 0,176 mg cafeic acid equivalent/ g of propolis. Flavonoids were evaluated by AlCl3 method and shown to be 9,839± 0,006 (EAP), 55,758 ± 0,128 (EEP) mg quercetin equivalent/ g of propolis. The free radical scavenging potential of the extracts was determined by the DPPH method, the IC50 are estimated at 0.0865 (BHT), 0.0223 (EAP), 0.0194 (EEP) mg/mL. We can conclude that propolis contains molecules that are considered first class of antioxidants and can be used for therapeutic applications, knowing that antioxidants contribute very effectively to disease prevention such as cancer, and cardiovascular disease.


Keywords: Propolis, aqueous extract, ethanolic extract, Antioxidant

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Soltani, E.-K., Mokhnache, K., & Charef, N. (2020). Polyphenol Contents and Antioxidant Activity of Ethanolic and Aqueous Algerian Propolis Extracts (Region of Serdj el ghoul). Journal of Drug Delivery and Therapeutics, 10(1), 1-4. https://doi.org/10.22270/jddt.v10i1.3797