Dietary Restriction: A Major Factor in Prophylaxis against Calcium Oxalate Urolithiasis

  • Kamel El-Reshaid Department of Medicine, Faculty of Medicine, Kuwait University, P O Box 24923, 13110 Safat, Kuwait
  • Shaikha Al-Bader Department of Medicine, Nephrology Unit, Amiri Hospital, Ministry of Health, Kuwait

Abstract

Urolithiasis (Ur) Is A Worldwide Problem That Affects All Groups Of Ages.  Nearly 80% Of Renal Stones Are Calcium Oxalate (Cao) And 50% Of The Affected Patients Have Recurrent Disease Within 10 Years.  Our Prospective Study Was Conducted Over 4 And ½ Years And Evaluated The Role Of Dietary Manipulation In Prophylaxis Against Cao Ur.  A Total Of 212 Patients With Recurrent Cao Ur, Who Lacked Anatomical Or Metabolic Derangement, Were Subjected To A Practical And Specific Diet.  The Latter Had: (A) Low Salt, Red-Meat And Green Leafy Vegetable, (B) Moderate Amounts Of Milk, Dairy Products, Poultry And Certain Fish-Items, And (C) High Water Intake (2 Liters/Day).  A Total Of 66/70 (96%), 87/108(88%) And 146/167(87.4%) Patients Were Stone-Free By The End Of 1, 2 And 3 Years Of Follow Up.  The Median Time For Stone-Free Duration Was 33 (28.7-37.3) Months.  Adding A Thiazide And Allopurinol To The 19 Patients Who Had Failed Dietary Prophylaxis Prevented Stone Formation In 16 More Patients Leaving Only 3 True Failures.  Four Patients Could Not Tolerate The Latter 2 Drugs For Allergy.  In Conclusion; Our Practical Dietary Modification Can Aid In Prophylaxis Against Cao Ur.   


Keywords: Diet, Calcium Oxalate, Urolithiasis, Urinary Tract Stones, Prophylaxis

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El-Reshaid, K., & Al-Bader, S. (2019). Dietary Restriction: A Major Factor in Prophylaxis against Calcium Oxalate Urolithiasis. Journal of Drug Delivery and Therapeutics, 9(6), 126-129. https://doi.org/10.22270/jddt.v9i6.3716