Taste masking Technologies: A Boon for Oral Administration of Drugs
Oral administration is widely used route of administration of drugs. The drug travels from the mouth, into the esophagus, then into the intestines. Sensing the taste is the major function of the tongue. In the formulation for pediatric & geriatric, bedridden & non-Cooperative patients, the main challenge to compounding pharmacist is to mask the taste of obnoxious and bitter drugs, result in patient non-compliance. Patients now expect and demand formulations that are pleasantly, or at least tolerable, flavored. This article reviews on taste-masking technologies and approaches for taste masking and bitterness reduction of dosage forms.
Keywords: Oral Administration, Drugs, Taste making, Taste bud
3. Shalini Sharma & Shaila Lewis, taste-masking technologies, International Journal of Pharmaceutical Sciences, 2010; 2(2): 6-13.
4. Gupta A.K., Practical Approaches for Taste Masking of Bitter Drug: A Review, International Journal of Drug Delivery Technology, 2010; 2(2): 56-61
5. Mackles, L., Chavkin, L., Tasteless forms of basic drugs prepared by absorption in situ. International journal of pharmaceutical innovations, 2014, 2(8), 1896-1918
6. Vijay A. Agrawal, taste abatement techniques to improve palatability of oral pharmaceuticals: A review, International journal of Pharma research and development,2008; 2(2): 22-30.
7. S. B. Ahire, A Review: Taste masking techniques in Pharmaceuticals, International journal of pharmaceutical sciences, 2015; 4(2): 1645-1656.
8. Jijo Abraham, Flowerlet Mathew: Taste masking of pediatric formulation: A review on technologies and recent trends and regulatory aspects 2014; 6(1): 12-18.
9. Vinod sonawane, Maria saiffee, Nitin Y. Shinde: An update of taste masking methods and evaluation techniques, Scholars research library 2010; 2(6): 1-12.
10. K.P. Sampath, Debjit Bhowmik, and Lokesh Deb, Recent trends in taste masking of bitter drugs: Review article, Journal of drug delivery research 2012; 1(1):1-9.
11. Lieberman H.A., Lachman L. (Eds.2). Chewable Tablets. In Pharmaceutical Dosage Forms, Vol-1(Tablet). New York: Marcel Dekker Inc.; 1981. p. 387-391.
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