Microwave Assisted Synthesis, Characterization and Anti-Tubercular Activity of 4-Quinolylhydrazone

  • Chandrakant V. Bisen
  • M. R. Patle
  • P.K. Rahangdale

Abstract

A series of 4-quinolylhydrazone derivatives was synthesized by reaction of 4-quinolylhydrazine and various substituted carboxaldehyde out of that most of the derivatives show significant antitubercular properties. The microwave assisted organic synthesis was applied to synthesize a series of 4-quinolylhydrazone derivatives. The characterizations of newly synthesized derivatives were done by modern analytical techniques like digital melting point apparatus, IR, NMR and mass spectroscopy.


Keywords: Mycobacterium tuberculosis, Hydrazone, Quinoline, Carboxaldehyde.

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Bisen CV, Patle MR, Rahangdale P. Microwave Assisted Synthesis, Characterization and Anti-Tubercular Activity of 4-Quinolylhydrazone. JDDT [Internet]. 30Aug.2019 [cited 24Feb.2020];9(4-A):95-7. Available from: http://jddtonline.info/index.php/jddt/article/view/3425