AN IN VITRO STUDY OF SYZYGIUM CUMINI SEED EXTRACT ON GLUCOSE UPTAKE ACTIVITY IN L-6 CELL LINES

SYZYGIUM CUMINI SEED EXTRACT ON GLUCOSE UPTAKE

  • Maneemegalai Sivaprakasam Government Arts and Science College (Women) [Formerly Bharathidasan University Constituent College for Women], Orathanadu- 614625, Thanjavur Dt, Tamil Nadu.
  • Narmatha M Government Arts and Science College (Women) Formerly Bharathidasan University Constituent College for Women], Orathanadu - 614625, Thanjavur Dt, Tamil Nadu

Abstract

Diabetes mellitus is the most common endocrine disorder. The plant Syzygium cumini has been used in traditional medicine for the treatment of diabetes. The present study investigated the effect of ethanol extract of S. cumini seeds on uptake of glucose by L-6 rat skeletal muscle cells. S. cumini seeds were extracted with varying solvents and quantitative phytochemical analysis was carried out, ethanol extract of seeds exhibited higher content of tested phytochemicals. The effect of different concentrations (300µg/ml – 1000µg/ml) of ethanol extract of seeds were studied on glucose uptake activity of L-6 rat skeletal muscle cells. It was observed that with the increase in concentration, the glucose uptake activity was also increased. The results of the study supports and demonstrates the antidiabetic potential of ethanol seed extracts of Syzygium cumini utilizing in vitro model.


KEY WORDS: Diabetes mellitus, Syzygium cumini, phytochemicals, glucose uptake, L-6 cells

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Author Biography

Narmatha M, Government Arts and Science College (Women) Formerly Bharathidasan University Constituent College for Women], Orathanadu - 614625, Thanjavur Dt, Tamil Nadu

Research Scholar, Department of Biochemistry

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How to Cite
Sivaprakasam, M., & M, N. (2019). AN IN VITRO STUDY OF SYZYGIUM CUMINI SEED EXTRACT ON GLUCOSE UPTAKE ACTIVITY IN L-6 CELL LINES. Journal of Drug Delivery and Therapeutics, 9(4-A), 256-259. https://doi.org/10.22270/jddt.v9i4-A.3419