New Frontier in the Treatment of Diabetes
Abstract
Diabetes mellitus is a group of metabolic diseases recognized by chronic hyperglycemia resulting from defects in secretion in insulin, insulin action or both. There are different types of diabetes like Type 1, type 2, gestational diabetes, secondary diabetes, wolfram syndrome and autoimmune polyglandular syndrome. Type 1 and type 2 diabetes are most common type of diabetes. Polydipsia, polyuria, polyphagia, weight loss slow wound healing, etc. are common symptoms of Diabetes. Diabetes can be genetic; autoimmune, medical related or even diet related. In this article causes and treatment of diabetes is discussed in detail. It includes glimpse of novel technologies like patches, pump and pens, etc. It also includes momentary of other treatment like oral and Injectable hypoglycemic drug and surgical treatments. A glance of latest innovation for measuring glucose level in body with help of sweat, breath and saliva are explained.
Keywords: Diabetes; Type 2 Diabetes Mellitus (TY2DM), Polydipsia, polyuria, polyphagia, clicksoft microinjection, insulin pen, v-go
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References
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2. Kenneth S Polonsky; “The past 200 yeasr in diabetes”; The New England Journal of Medicine.
3. SamreenRiaz; “Diabetes Mellitus”; Scientific Research and Essay; Vol 4(5); May 2009; page no. 367-373.
4. Anees A Siddiqul, et al; “Diabetes: Mechanism, Pathophysiology and Management: A Review”; International Journal of drug development and research.
5. Abdulfatai B Olokoba, Et al; “type 2 Diabetes Mellitus: A review of current trends”; Oman Medical Journal; July 27(4); page no 269-273.
6. Seema A Kaveeshwar and Jon Cornwall; “The current state of diabetes mellitus in India”; The Australian Medical Journal; 2014, 7(1); page no 45-48.
7. Juan José Marín-Peñalver, et al; “Update on the treatment of type 2 diabetes mellitus”; World journal of diabetes; Baishideng Publishing Group; 2016 September 15; 7(17): page no 354-395.
8. Priya Raina, et al; “Novel Technologies Mark the Future of Insulin”; American journal of Pharmtech research; 2017; 7(1); page no 100-120.
9. Philip r. Schauer, md, et al; “metabolic surgery for treating type 2 diabetes mellitus: now supported by the world's leading diabetes organizations”; Cleveland clinic journal of medicine volume 84 • supplement 1 July 2017 page no s47-s56
10. Maneesh khaana, et al; “advanced delivery device- painless intradermal delivery system the novel Clicksoft microinjection; Drug Delivery Technology February 2009 Vol 9 No 2.
11. Rosemarie Lajara, et al; “Use of V-Go_ Insulin Delivery Device in Patients with Sub-optimally Controlled Diabetes Mellitus: A Retrospective Analysis from a Large Specialized Diabetes System” Diabetes Ther (2015) 6:531–545
12. KD Tripathi; “Essential of Medical Pharmacology”; Jaypee brother’s medical publishers (P) ltd, Sixth Edition, Chapter-19; page no 254-274.
13. Mahamood Edavalath and Jeffrey W Stephens; “Liraglutide in treatment of type 2 diabetes mellitus: clinical utility and patient perspective”; Patient preference and Adherence; 2010:4; Dove press; Page no 61-68.
14. Habtamu Wondifraw Baynest; “Classification, pathophysiology, Diagnosis and management of diabetes mellitus”; journal of diabetes and metabolism; 2015; volume6; issue5; April 30, 2015.
15. Terri L. levien and E. Baker; “ New drugs in development for the treatment of Diabetes”; Diabetes Spectrum; volume 22, number 2; 2009; Page no.92-105
16. BERIT L., et al.; “Current and Future Perspectives on Alginate Encapsulated Pancreatic Islet” STEM CELLS TRANSLATIONALMEDICINE 2017;6: page no1053–1058
17. Danielle Bruen, et al; “Glucose Sensing for Diabetes Monitoring: Recent Developments” Sensors 2017, issue 17.
18. Sempionatto, J.R.; et al. “Eyeglasses based wireless electrolyte and metabolite sensor platform” Lab Chip 2017, 17, 1834–1842.
19. Jiang, C.; et al. “A portable real-time ring down breath acetone analyzer: Toward potential diabetic screening and management” Sensors 2016, 16, 1199.
20. Yamada, K.; et al. “Measurement of natural carbon isotopic composition of acetone in human urine” Anal-Bioanal. Chem. 2016, 408, 1597–1607.
21. Bandodkar, A.J.; Wang, J. “Non-invasive wearable electrochemical sensors: A review” Trends Biotechnol. 2014, 32, 363–371.
22. Kim, J.; et al “Non-invasive mouth guard biosensor for continuous salivary monitoring of metabolites” Analyst 2013, 139, 1632–1636.
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Bhatt A, Vyas A, Shah D. New Frontier in the Treatment of Diabetes. JDDT [Internet]. 15Oct.2019 [cited 29Sep.2020];9(5-s):178-87. Available from: http://jddtonline.info/index.php/jddt/article/view/3375
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