Titration Design: An Important Key in Drug Dose Determination

  • Rada Santosh Kumar GITAM Institute of Pharmacy, GITAM (Deemed to be University)
  • R Venkata Sandhya

Abstract

Drug titration is the process of adjusting the dose of a medicine for the maximum benefits without adverse effects. To determine the optimum dose range the clinical trials are carried out and it is divided into two types of study design. The parallel type study design and titration type study design. The titration studies provide the information about the cumulative effects of the drug. Titration designs are mainly used in dose determining especially in insulin, anticonvulsants, anti-depressants, and sedatives. In the analysis of titration design, the phase I, II, III clinical trials are carried out to determine the dose-response relationship, safety and efficacy of the drug.

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Author Biography

R Venkata Sandhya

GITAM Institute of Pharmacy, GITAM (Deemed To Be University) Rushikonda, Visakhapatnam-530045, Andhra Pradesh, India.

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How to Cite
Santosh Kumar, R., & Venkata Sandhya, R. (2019). Titration Design: An Important Key in Drug Dose Determination. Journal of Drug Delivery and Therapeutics, 9(4-s), 826-828. https://doi.org/10.22270/jddt.v9i4-s.3374

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