Antagonistic Property of Selected Herbal Combination for Substitute of Synthetic Antimicrobial Agents

  • Pechimuthu Karpagam
  • G Manonmani

Abstract

The emergence and spread of bacterial strains of multi- drug resistant continues to challenge the healthcare sector of both developed and developing countries. Owing to this problem and concerning the side effects of synthetic antimicrobial agents, the current work was done with medicinal plants. The plant materials such as Terminalia bellerica, Withania somnifera, Madhuca longifolia and Sygyzium cumini was selected based on its potent antimicrobial activity. The best combination of the selected plants was evaluated for their antimicrobial activity. The phytochemical analysis of the selected combination showed the presence of phytoconstituents that are responsible for their biocidal activity. The Minimum inhibitory concentration (MIC) was studied for the selected herbal combination. The results recommend the use of selected plants at their best combination as a substitute to synthetic agents that can effectively prevent the microbial infestation.


Keywords: Antimicrobial activity, Cross infection, Medicinal Plant, MIC, Phytochemical.

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Author Biographies

Pechimuthu Karpagam

Assistant Professor, Department of Costume Design and Fashion, PSG College of Arts and Science, Coimbatore 641014, India.

G Manonmani

Research Supervisor, Department of Home Science, Mother Teresa University for Women, Coimbatore 641002, TN, India.

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How to Cite
Karpagam, P., & Manonmani, G. (2019). Antagonistic Property of Selected Herbal Combination for Substitute of Synthetic Antimicrobial Agents. Journal of Drug Delivery and Therapeutics, 9(4-A), 53-56. https://doi.org/10.22270/jddt.v9i4-A.3262