Aphrodisiac activity of hydro-alcoholic extract of Celosea argentea dried seeds in male rats
Objective: The study was aimed at to investigate the aphrodisiac activity of hydro-alcoholic extract of Celosea argentea dried seeds (Amaranthacea) in male albino rats in different doses. Material and methods: The animals were selected in the present investigation on the basis of their performance in the Copulatory arena and runway apparatus. After selection animal (n=6), they were treated with extract of Celosea argentea (200 and 400 mg/kg) and sildenafil citrate (5mg/kg) orally. While the control animals were given with normal water. All the treatments were given for 21days. Sexual motivation and mating behavior parameters in male rats were monitored on 11th and 21st day of treatment pairing with receptive females. After termination of drug treatment the parameter such as sexual motivation, mating behavior, serum testosterone level, histological examination of testes, relative organ weight and body weight percent were evaluated. Result: The hydro-alcoholic extract of celosia argentea seeds showed a significant increase in mating behavior, serum testosterone levels, testes- body weight ratio as compared to vehicle control, while at the dose of 400mg/kg of Celosea argentea seeds extract assume closer resemblance of above parameters with the standard used. Conclusion: The results of the study strongly suggest that the seed extract of Celosia argentea have good aphrodisiac activity.
Keywords: Aphodisiac, Celosea argentea, sexual motivation, mating behavior, Serum testosterone level
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