Antioxidant Potential of Psoralea corylifolia and Psoralea esculenta seeds: Comparative Study
The Psoralea corylifolia L. & Psoralea esculenta seeds are traditionally used herbal medicine, but its comparative antioxidant activity has not been studied. The methanolic crude extracts of Psoralea corylifolia & Psoralea esculenta seeds were screened for their free radical scavenging properties using ascorbic acid as standard antioxidant. Free radical scavenging activity was evaluated using 1,1-diphenyl-2-picryl hydrazyl (DPPH) free radical. The overall antioxidant activity of Psoralea corylifolia was found to be the strongest. The IC50 values of the extracts found 0.14 ± 0 & 0.05 ± 0 mg/l respectively. The ascorbic acid levels found19.3 ± 0.10 &11.7 ± 0.49 mg/100g andthe carotenoids content were observed 28.65 ± 0.24 &16.82 ± 1.16 mg/100g in plant extracts. The highest total phenols content were found to be in Psoralea corylifolia with the value 31.2 ± 0.24 mg/g.The present study reveals that the selected plants would exert several beneficial effects by virtue of their antioxidant activity and may be taken for drug formulation.
Keywords: 1,1-diphenyl-2-picryl hydrazyl, antioxidant, phenol, radical scavenger.
2. Halliwell B (1994). Free radicals, antioxidants, and human disease: curiosity, cause, or consequence? Lancet. 344: 721-724.
3. Pourmorad F, Hosseinimehr SJ, Shahabimajd N (2006). Antioxidant activity, phenols, flavanoid contents of selected Iranian medicinal plants. S. Afr. J. Biotechnol. 5: 1142-1145.
4. Duh PD, Tu YY, Yen GC (1999). Antioxidants activity of aqueous extract of Harnjyur (Chrysanthemum morifoliumRamat).Lebensmwiss Technol. 32: 269-277.
5. Raja Sudarajan N, Ahamad H, Kumar V (2006). CytisusscopariusLink-A natural antioxidant. 6: 1-7
6. Cao G, Sofic ER, Prior RL (1996). Antioxidant capacity of tea and common vegetables. J. Agric. Food Chem. 44: 3426-3431.
7. Braca A, Sortino C, Politi M (2002). Antioxidant activity of flavonoids from Licanialicaniaeflora. J. Ethnopharmacol. 79: 379-381.
8. Yen GC, Duh PD (1994). Scavenging effect of methanolic extracts of peanut hulls on free-radical and active oxygen species. J. Agric. Food Chem. 42: 629-632.
9. Cakmak I, Marschner H (1992). Magnesium deficiency and high light intensity enhance activities of superoxide dismutase, ascorbate peroxidase and glutathione reductase in bean leaves. Plant Physiol. 98:1222-1227.
10. Jensen A (1978).Chlorophyll and carotenoids. In: Hallebust JA, Craigie JS. (eds). Handbook of Physiochemical and Biochemical Methods. Cambridge University Press, Cambridge, UK, pp. 5-70.
11. McDonald S, Prenzler PD, Autolovich M, Robards K (2001). Phenolic content and antioxidant activity of olive extracts. Food Chem. 73: 73- 84.
12. Koleva II, Van Beek TA, Linseen JPH, de Groot A, Evstatieva LN (2002). Screening of plant extracts for antioxidant activity: a comparative study on three testing methods. Phytochem.Anal.13:8- 17.
13. Suresh PK, Sucheta S, Sudarshana VD, Selvamani P, Latha S (2008).Antioxidant activity in some selected Indian medicinal plants. Afr. J. Biotechnol. 7: 1826-1828.
14. Kanatt SR, Chander R, Sharma A (2007). Antioxidant potential of mint (MenthaspicataL.) in radiation- processed lamb meat. Food Chem. 100: 451-458.
15. Beyer RE (1994). The role of ascorbate in antioxidant protection of biomembranes: interaction with vit-E and coenzyme. Q. J. Bioen. Biomemb. 24: 349-358.
16. Aqil F, Ahmed I, Mehmood Z (2006). Antioxidant and free radical scavenging properties of twelve traditionally used Indian medicinal plants. Turk. J. Biol. 30:177-183.
17. Malencic D, Gasic O, Popovic M, Boza P (2000).Screening for antioxidant properties of Salvia reflexahornem.Phytother. Res. 14: 546-548.
18. Stivala LA, Savio M, Cazzalini O, Pizzala R, Rehak L, Bianchi L, Vannini V, Prosperi E (1996). Effect of _-carotene on cell cycle progression of human fibroblasts.Carcinogen. 17: 2395-2401.
19. Lee J, Jiang S, Levine N, Watson R (2000). Carotenoid supplementation reduces erythema in human skin after simulated solar radiation exposure. PSEMB. 2231:170-174.
20. Cook NC, Samman S (1996). Flavonoids-chemistry, metabolism, cardioprotective effects and dietary sources.Nutr.Biochem.7:66- 76.
21. Rice-Evans CA, Miller NJ, Paganga G (1997). Antioxidant properties of phenolic compounds.Trend. Plant Sci. 4:152-159.
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (SeeÂ The Effect of Open Access).