Antioxidant Potential of Psoralea corylifolia and Psoralea esculenta seeds: Comparative Study

  • Neeraj Singh Faculty of Pharmacy, Bhagwant University, Ajmer, Rajasthan, India
  • Girendra Kumar Gautam Faculty of Pharmacy, Bhagwant University, Ajmer, Rajasthan, India
  • Akash Ved Goel College of Pharmacy, Lucknow, UP, India

Abstract

The Psoralea corylifolia L. & Psoralea esculenta seeds are traditionally used herbal medicine, but its comparative antioxidant activity has not been studied. The methanolic crude extracts of Psoralea corylifolia & Psoralea esculenta seeds were screened for their free radical scavenging properties using ascorbic acid as standard antioxidant. Free radical scavenging activity was evaluated using 1,1-diphenyl-2-picryl hydrazyl (DPPH) free radical. The overall antioxidant activity of Psoralea corylifolia was found to be the strongest. The IC50 values of the extracts found 0.14 ± 0 & 0.05 ± 0 mg/l respectively. The ascorbic acid levels found19.3 ± 0.10 &11.7 ± 0.49 mg/100g andthe carotenoids content were observed 28.65 ± 0.24 &16.82 ± 1.16 mg/100g in plant extracts. The highest total phenols content were found to be in Psoralea corylifolia with the value 31.2 ± 0.24 mg/g.The present study reveals that the selected plants would exert several beneficial effects by virtue of their antioxidant activity and may be taken for drug formulation.

Keywords: 1,1-diphenyl-2-picryl hydrazyl, antioxidant, phenol, radical scavenger.

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Author Biographies

Neeraj Singh, Faculty of Pharmacy, Bhagwant University, Ajmer, Rajasthan, India

Faculty of Pharmacy, Bhagwant University, Ajmer, Rajasthan, India

Girendra Kumar Gautam, Faculty of Pharmacy, Bhagwant University, Ajmer, Rajasthan, India

Faculty of Pharmacy, Bhagwant University, Ajmer, Rajasthan, India

Akash Ved, Goel College of Pharmacy, Lucknow, UP, India

Goel College of Pharmacy, Lucknow, UP, India

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Published
2019-06-26
How to Cite
1.
Singh N, Gautam GK, Ved A. Antioxidant Potential of Psoralea corylifolia and Psoralea esculenta seeds: Comparative Study. JDDT [Internet]. 26Jun.2019 [cited 8Sep.2024];9(3-s):740-3. Available from: http://jddtonline.info/index.php/jddt/article/view/2985