Overview of Transdermal Medicated Patches with its research updates in preceding years
Innovations in transdermal drug delivery systems (TDDS) is an important influence to medical practice by providing advances in the delivery of treatment with existing conventional drugs and novel drugs. Transdermal drug delivery is one of the most promising methods for drug application. It has several benefits over conventional system to offer sustained drug release, avoidance of first pass effect, patient compliance, ease of application and removal in case of toxicity as well as decrease in the side effects as compared with conventional therapy. Transdermal patches are dosage forms which transport drug to viable epidermal and dermal tissues of the skin for local therapeutic effect while a very major fraction of drug is transported into the systemic blood circulation. Skin penetration enhancement techniques have been developed to improve bioavailability and increase the range of drugs for which topical and transdermal delivery. The purpose of this review is to introduce transdermal patches including type of transdermal patches, components of transdermal patches, method of preparation of TDDS, evaluation parameters, researches and development done on TDDS in last decade etc.
Keywords: Transdermal Drug Delivery System, Permeation Enhancers, Transdermal Patch, Polymer Matrix.
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