Preparation and Evaluation of Diltiazem Hydrochloride Controlled Release Matrix Tablets Employing Aegle marmelos Gum: A Novel Natural Controlled Release Polymer

  • Rada Santosh Kumar GITAM Institute of Pharmacy, GITAM (Deemed to be University), Rushikonda, Visakhapatnam, A.P 530045, INDIA.
  • Ch. Pratibhanusha SrinivasaRao College of Pharmacy, P.M.Palem, Visakhapatnam, A.P 530040, INDIA
DOI https://doi.org/10.22270/jddt.v9i3.2920

Abstract

Oral Drug Delivery is considered as the holy grail of drug delivery due to its convenience which resulted in high patient compliance. Of all the drug delivery systems that have been explored, oral drug delivery is the most preferred option for systemic delivery of drug via various pharmaceutical products of different dosage forms. The advantage of administering a single dose of drug which is released over an extended period of time, instead of administering numerous doses, is now a day’s area of interest for formulation scientists in the pharmaceutical industry. For this reason, the conventional dosage forms of drugs are rapidly being replaced by the new and the novel drug delivery systems. Amongst these, the controlled release dosage forms have gradually gained medical acceptance and became extremely popular in modern therapeutics. The aim of the present work is to isolate Aegle marmelos gum and use it as a controlled release polymer in the formulation of diltiazem hydrochloride controlled release tablets.


Keywords: Isolation, Controlled release, Aegle marmelos Gum.

Downloads

Download data is not yet available.

Author Biographies

Rada Santosh Kumar, GITAM Institute of Pharmacy, GITAM (Deemed to be University), Rushikonda, Visakhapatnam, A.P 530045, INDIA.

GITAM Institute of Pharmacy, GITAM (Deemed to be University), Rushikonda, Visakhapatnam, A.P 530045, INDIA.

Ch. Pratibhanusha, SrinivasaRao College of Pharmacy, P.M.Palem, Visakhapatnam, A.P 530040, INDIA

SrinivasaRao College of Pharmacy, P.M.Palem, Visakhapatnam, A.P 530040, INDIA

References

1. Dave B.S, Aoni N, A.F. Patel. M.M, AAPS Pharma Sci Tech, 2004, 5-34.
2. Indian Pharmacopoeia, The Indian Pharmacopoeia Commission, Ghaziabad, Ministry Of Health and Family Welfare, Government of India, New Delhi, 2007, 1, 182.
3. Higuchi. T. J. Pharm Sci, 1963, 52; 1145-9.
4. Koresmeyer.R, Gurng R, Int. J, Pharm, 1983, 15; 25-35.
5. Peppas. N.A, Pharma Acta Hel. V, 1985, 60; 110-1.
Statistics
72 Views | 167 Downloads
How to Cite
1.
Santosh Kumar R, Pratibhanusha C. Preparation and Evaluation of Diltiazem Hydrochloride Controlled Release Matrix Tablets Employing Aegle marmelos Gum: A Novel Natural Controlled Release Polymer. JDDT [Internet]. 22May2019 [cited 26Jan.2021];9(3):487-92. Available from: http://jddtonline.info/index.php/jddt/article/view/2920
Issue
Vol 9 No 3 (2019): Volume 9, Issue 3, May-June 2019
Section
Research
Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Authors who publish with this journal agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).