Evaluation of prescription pattern and compliance in kashmiri women with polycystic ovarian syndrome
Background: Polycystic ovary syndrome (PCOS) is one of the most common endocrine system disorder affecting women of reproductive age. As there are a few studies with inconsistent data available in the literature regarding the prescription pattern and compliance of drugs in patients with PCOS, both within and outside India, the present study was undertaken to generate some valid and useful data regarding these parameters.
Objective: Evaluation of drug utilization and assessment of prescribing patterns and patient compliance among Kashmiri women with polycystic ovary syndrome.
Materials and Methods: This study was a prospective, observational and cross-sectional study, which was carried out on Kashmiri females diagnosed with PCOS as per Rotterdam criteria of 2003. Patients attending Srinagar based hospitals and clinics over a period of nine months. Information was collected through personal interviews using a pre-validated, self-administered data collection tool. The prescribing patterns of drugs were evaluated by comparison with Endocrine Society Clinical Practice Guidelines. Patient compliance with prescribed medicines was assessed using modified Morisky 8-Item Medication Adherence Questionnaire.
Results: Drugs prescribed to the study patients included oral contraceptive pills (OCPs) 57(46.34%), insulin sensitizers 75 (60.97%), anti-androgen 37 (30.08%), anti-estrogens 1 (0.81%), progestins 10 (8.13%), dopaminergic agonists 7 (5.69%), steroids 2 (1.62%) and statins 1(0.81%). 50 (40.65%) patients were highly adherent to their prescribed medications. Conclusion: The study revealed that nature of drugs prescribed to the study population was in consonance with the established standard guidelines. Most of the women were highly adherent to their prescribed medications.
Keywords: PCOS, prescription, drug adherence.
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