Pharmacognostic Investigation and HPTLC Fingerprinting of a Siddha Polyherbal Drug, Padai chankaran

  • B Neethu Kannan
  • V Gayathri Devi
  • John Anitha
  • GS Lekha
  • M Natarajan
  • A Kanagarajan

Abstract

The present study aims to establish the quality and purity of a Siddha formulation, Padai chankaran by laying down various pharmacognostic parameters, physico-chemical constants and HPTLC fingerprint profiles. Padai chankaran is a Siddha polyherbal preparation comprised of Catunaregum spinosa – root bark, C. spinosa – seed and Alangium salvifolium – root bark as the ingredients. The formulation is used as an external application, having astringent, anthelmintic and antiseptic activities that supports in healing of ulcers and dermatological diseases. Powder microscopy studies and physico-chemical analysis were carried out. Also, an attempt has been made to develop a HPTLC method for phytochemical fingerprinting and the mobile phase Toluene: Ethyl acetate: Formic acid (5: 2: 0.1) gave the best resolution for various components. Hence, the aforesaid analyses confirmed the purity and quality of the Siddha formulation for their future applications.


Keywords: Padai chankaran, powder microscopy, physico-chemical, HPTLC studies

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Neethu Kannan, B., Gayathri Devi, V., Anitha, J., Lekha, G., Natarajan, M., & Kanagarajan, A. (2019). Pharmacognostic Investigation and HPTLC Fingerprinting of a Siddha Polyherbal Drug, Padai chankaran. Journal of Drug Delivery and Therapeutics, 9(3-s), 317-323. https://doi.org/10.22270/jddt.v9i3-s.2845