Synthesis, Characterization and Biological activities of 2-Amino-3-Methyl pyridine New Dithiocarbamate metal complexes

  • S. Khajavali Department of Chemistry, Rayalaseema University, Kurnool, Andhra Pradesh, India
  • A. Jayaraju Department of Chemistry, Dravidian University, Kuppam, Andhra Pradesh, India
  • J. Sreeramulu Department of Chemistry, S.K.University, Anantapur, Andhra Pradesh, India

Abstract

Dithiocarbamates are a class of sulfur-based metal-chelating compounds with various applications in medicine. A new series of new transition metal [Cu(II), and Ni(II)] complexes of dithiocarbamates were synthesized from 2-Amino-3-Methyl pyridine and Carbon disulfide and further characterized. The investigation of these complexes confirmed that the stability of metal–ligands coordination through, S&S,N atoms as bidendate chelates.. It is necessary to understand the binding properties in developing new potential Protein targeting against neurological disorders.


Keywords:2-Amino-3-Methylpyridine,MetalComplexes,Dithiocarbamates,neurological disorders.

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Author Biographies

S. Khajavali, Department of Chemistry, Rayalaseema University, Kurnool, Andhra Pradesh, India

Department of Chemistry, Rayalaseema University, Kurnool, Andhra Pradesh, India

A. Jayaraju, Department of Chemistry, Dravidian University, Kuppam, Andhra Pradesh, India

Department of Chemistry, Dravidian University, Kuppam,  Andhra Pradesh, India

J. Sreeramulu, Department of Chemistry, S.K.University, Anantapur, Andhra Pradesh, India

Department of Chemistry, S.K.University, Anantapur, Andhra Pradesh, India

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How to Cite
Khajavali, S., Jayaraju, A., & Sreeramulu, J. (2019). Synthesis, Characterization and Biological activities of 2-Amino-3-Methyl pyridine New Dithiocarbamate metal complexes. Journal of Drug Delivery and Therapeutics, 9(3-s), 36-39. https://doi.org/10.22270/jddt.v9i3-s.2742