Synthesis, Characterization and Biological activities of 2-Amino-3-Methyl pyridine New Dithiocarbamate metal complexes
Dithiocarbamates are a class of sulfur-based metal-chelating compounds with various applications in medicine. A new series of new transition metal [Cu(II), and Ni(II)] complexes of dithiocarbamates were synthesized from 2-Amino-3-Methyl pyridine and Carbon disulfide and further characterized. The investigation of these complexes confirmed that the stability of metal–ligands coordination through, S&S,N atoms as bidendate chelates.. It is necessary to understand the binding properties in developing new potential Protein targeting against neurological disorders.
 Aly AAM; El-Meligy MS; Zidan ASA. Transition Met. Chem., 1989; 14:366–368.
. AI El-Said; AAM Aly. Synth. React. Inorg. Met.-Org. Chem., 1990; 1059–1069.
. Ajibade PA; Kolawole GA. J. Coord. Chem., 2008; 61(21):3367–3374.
. Hulanicki A. Talanta, 1967; 14:1371–1392.
 Coucouvanis D. Prog. Inorg. Chem., 1970; 11:233–371.
 Manoussakis G; C Bolos; L Ecateriniadou; C Sarris. Eur. J. Med. Chem., 1987; 22:421–425.
 Giovagnini L; Marzano C; Bettio F; Fregona D. J. Inorg. Biochem., 2005; 99:2139–2150.
 Manohar A; Ramalingam K; R Thiruneelakandan; G Bocelli; L Righi. Z. Anorg. Allgem. Chem., 2006; 632:461–464.
 Pastorek R; Kameníček J; Husárek J; Slovák V; Pavlíček M. J. Coord. Chem., 2007; 60(5):485–494.
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