A Review: Formulation and Characterization of Fast Dissolving Tablet of Carvidilol

  • Ankit Sharma Department of pharmaceutics, Jaipur College of Pharmacy, Jaipur, Rajasthan, INDIA
  • Avinash Kumar Gupta
  • Manish Kumar Gupta
  • Vijay Sharma

Abstract

Carvedilol a poorly water soluble drug undergoes extensive first pass metabolism, which reduces its bioavailability to 25-30%. Fast dissolving tablets of Carvedilol were prepared with the purpose of delivering the drug directly into the systemic circulation and bypassing the hepatic first pass metabolism with a concomitant increase in bioavailability. The solubility of Carvedilol was improved by forming inclusion complex with cyclodextrin which was then further used for the formulation of Fast dissolving tablet.


Keywords: Carvedilol, Superdisintegrats, Fast dissolving Tablets and FDTs.

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Author Biography

Ankit Sharma, Department of pharmaceutics, Jaipur College of Pharmacy, Jaipur, Rajasthan, INDIA

Department of pharmaceutics, Jaipur College of Pharmacy, Jaipur, Rajasthan, INDIA

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How to Cite
Sharma, A., Gupta, A. K., Gupta, M. K., & Sharma, V. (2019). A Review: Formulation and Characterization of Fast Dissolving Tablet of Carvidilol. Journal of Drug Delivery and Therapeutics, 9(3), 749-752. https://doi.org/10.22270/jddt.v9i3.2738

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