Method development and validation of Sofosbuvir and iedipasvirin by HPLC: A Review
The aim of this review article is emphasizing on development and validation protocol which will used to develop and validate accurate, simple, selective and specific spectrophotometric methods for the determination of Sofosbuvir (SOF) and Ledipasvir (LDV) in pure and in their dosage forms. Thus it is necessary to develop methods for analysis with the help of number of analytical techniques which are available for the estimation of the drugs in combination. The analyst were determine the Specific, accurate, simple, selective and stability-indicating RP-HPLC method is developed and validated for simultaneous determination of sofosbuvir and ledipasvir in tablet dosage form.
Keywords: Sofosbuvir, Ledipasvir, RP-HPLC, Method development, Method validation.
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